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L6135

Sigma-Aldrich

Lectin from Arachis hypogaea (peanut)

biotin conjugate, lyophilized powder

Sinônimo(s):

PNA, Peanut agglutinin

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About This Item

Código UNSPSC:
12352202
NACRES:
NA.32

conjugado

biotin conjugate

Nível de qualidade

forma

lyophilized powder

peso molecular

120 kDa

composição

Protein, ≥80% Lowry

Extensão da rotulagem

~3 mol biotin per mol protein

técnica(s)

blood typing: suitable
fractionation: suitable

solubilidade

water: 1.00-1.10 mg/mL, clear to slightly hazy, colorless

temperatura de armazenamento

2-8°C

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Descrição geral

Peanut lectin (PNA) is a lectin or an agglutinin from the legume, Arachis hypogaea, found in peripheral venous blood in humans after ingestion of peanuts. PNA lectin is specific to the galactosyl (β-1,3) N-acetylgalactosamine.

Aplicação

Lectin from Arachis hypogaea (peanut) has been used:
  • in enzyme-linked micro plate assay to detect β-D-galactose-N-acetylglucosamine
  • in Immunohistochemical double staining
  • Immunohistochemical double staining for the detection of germinal centers
  • in enzyme-linked microplate assayto detect β-D-galactose-N-acetylglucosamine

Ações bioquímicas/fisiológicas

Lectin from Arachis hypogaea (peanut) functions as an antigenic determinant for Thomsen-Friedenreich antigen (TF) and as mitogen for colorectal cancer stimulation cell division in normal colonic epithelium. It is therefore used as tumor marker.
PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.

Embalagem

Package size based on protein content.

forma física

Contains sodium citrate

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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