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F3385

Sigma-Aldrich

Fetuin from fetal bovine serum

lyophilized powder, BioReagent, suitable for cell culture

Sinônimo(s):

Fetuin from fetal calf serum

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About This Item

Número CAS:
9014-81-7
Número CE:
232-762-7
Número MDL:
MFCD00131055
Código UNSPSC:
12352202
NACRES:
NA.75

linha de produto

BioReagent

forma

lyophilized powder

peso molecular

48.4 kDa

técnica(s)

cell culture | mammalian: suitable

Impurezas

≤0.3% free N-acetylneuraminic acid

solubilidade

H2O: 1 mg/mL

temperatura de armazenamento

2-8°C

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Descrição geral

Fetuin from fetal bovine serum is a plasma glycoprotein. It is a 64 kDa glycoprotein, which is produced by the liver and adipose tissue.
A glycoprotein derived from FBS that is used as Fetuin has been used at a concentration of 500 mg/ml to supplement serum free F12 medium (along with insulin, transferrin and 2-mercaptoethanol) in culture of embryonal carcinoma cells.

Aplicação

Fetuin from fetal bovine serum has been used:
  • as a substrate to determine neuraminidase activity
  • to validate the specificity of sialidases
  • to stabilize m-calpain

Ações bioquímicas/fisiológicas

Fetuin acts as an inhibitor of insulin receptor tyrosine kinase. It modulates bone remodeling and calcium metabolism. Fetuin regulates vascular calcification, insulin resistance, protease activity control, keratinocytes migration and breast tumor cell proliferative signaling. It functions as a biomarker for neurodegenerative diseases. Fetuin exhibits anti-inflammatory property.

Nota de preparo

Prepared by ammonium sulfate fractionation of fetal bovine serum by the method of Pederson, K.O., J. Phys. and Colloid Chem., 51, 164 (1947).

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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