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H7166

Sigma-Aldrich

IL-3 human

HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture

Sinônimo(s):

Interleukin-3 human, IL-3

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10 μG
R$ 2.636,00

R$ 2.636,00


Disponível para enviar em07 de abril de 2025Detalhes



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10 μG
R$ 2.636,00

About This Item

Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.77

R$ 2.636,00


Disponível para enviar em07 de abril de 2025Detalhes


Nome do produto

Interleukin-3 human, IL-3, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

fonte biológica

human

Nível de qualidade

recombinante

expressed in HEK 293 cells

Ensaio

>95% (SDS-PAGE)

Formulário

lyophilized powder

potência

≤2 ng/mL EC50

qualidade

endotoxin tested

peso molecular

dimer 17-45 kDa (glycosylated)

embalagem

pkg of 10 μg

fabricante/nome comercial

HumanZyme

técnica(s)

cell culture | mammalian: suitable

Impurezas

<1 EU/μg

nº de adesão UniProt

temperatura de armazenamento

−20°C

Informações sobre genes

human ... IL3(3562)

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Ações bioquímicas/fisiológicas

Interleukin-3 (IL-3) is a multifunctional protein, originally called colony forming unit-stimulating activity (CFU-SA), and is produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 has been shown to induce colony formation of macrophages, neutrophils, mast cells, and megakaryocytes from agar-suspended bone marrow cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and to induce IgG secretion from activated B cells. Other synonyms for IL-3 include pan-specific hemopoietin, multicolony stimulating factor, mast cell growth factor, burst promoting activity, histamine-producing cell stimulating factor, P cell stimulating factor, and WEHI-3 factor.
Interleukin-3 is a multifunctional protein produced by activated T lymphocytes. IL-3 supports the formation of multilineage colonies in the early development of multipotent hematopoietic progenitor cells. IL-3 also interacts with IL-2 to stimulate growth of T lymphocytes and induce IgG secretion from activated B cells.

forma física

Lyophilized from a 0.2 μm filtered solution of 1x PBS.

Nota de preparo

HumanKine Interleukin-3 (IL-3), expressed in human HEK 293 cells, is a glycosylated monomer with an apparent molecular mass of 17-45 kDa due to glycosylation, which is absent when this cytokine is expressed in E. coli. Production in human HEK 293 cells offers authentic glycosylation which contributes to stability in cell growth media and other applications.

Nota de análise

The activity was determined by the dosedependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Informações legais

HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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