1.06447

Citrato de sódio tribásico

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS, E 331

• Sinônimo(s): Citrato trissódico, Ácido cítrico
• Fórmula linear: HOC(COONa)(CH₂COONa)₂ · 2H₂O
• Número CAS: 6132-04-3
• Peso molecular: 294.10
• Beilstein: 6104939
• Número MDL: MFCD00150031
• Código UNSPSC: 12352107
• Número E: E331
• Número do índice EC: 200-675-3

Propriedades

• Agency: BP; ChP; JP; Ph. Eur.; USP; suitable for SM 4500 - NH3
• Nível de qualidade: 500
• linha de produto: EMPROVE^® EXPERT
• Formulário: solid
• Características: RNase and DNase free
• Impurezas: endotoxins, low
• pH: 7.5-9.0 (25 °C, 50 g/L in H₂O)
• pKa: (1) 3.1, (2) 4.8, (3) 6.4
• pf: 150 °C (anhydrous substance); >300 °C (lit.)
• aplicação(ões): liquid formulation; ophthalmics; parenterals; pharma/biopharma processes; pharmaceutical; semi-solid formulation; solid formulation
• temperatura de armazenamento: 2-30°C
• cadeia de caracteres SMILES: O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
• chave InChI: NLJMYIDDQXHKNR-UHFFFAOYSA-K

Descrição

Descrição geral

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Aplicação

tri-Sodium citrate dihydrate is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Informações legais

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable