SML0669

VUF11207 trifluoroacetate salt

≥98% (HPLC)

• Synonym(e): (E)-N-(3-(2-Fluorophenyl)-2-methylallyl)-3,4,5-trimethoxy-N-(2-(1-methylpyrrolidin-2-yl)ethyl)benzamide trifluoroacetate salt, N-[(2E)-3-(2-Fluorophenyl)-2-methyl-2-propen-1-yl]-3,4,5-trimethoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-benzamide trifluoroacetate salt
• Empirische Formel (Hill-System): C₂₇H₃₅FN₂O₄ · C₂HF₃O₂
• CAS-Nummer: 1378524-41-4
• Molekulargewicht: 584.60
• MDL-Nummer: MFCD26961112
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 329825579
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Lagerbedingungen: desiccated; protect from light
• Farbe: white to beige
• Löslichkeit: H₂O: 5 mg/mL, clear (warmed)
• Lagertemp.: −20°C
• SMILES String: O=C(N(CCC1N(C)CCC1)C/C(C)=C/C2=C(F)C=CC=C2)C3=CC(OC)=C(OC)C(OC)=C3.OC(C(F)(F)F)=O
• InChI: 1S/C27H35FN2O4.C2HF3O2/c1-19(15-20-9-6-7-11-23(20)28)18-30(14-12-22-10-8-13-29(22)2)27(31)21-16-24(32-3)26(34-5)25(17-21)33-4;3-2(4,5)1(6)7/h6-7,9,11,15-17,22H,8,10,12-14,18H2,1-5H3;(H,6,7)/b19-15+;
• InChIKey: GZXNWMFPSYCITC-QTCZRQAZSA-N

Beschreibung

Biochem./physiol. Wirkung

VUF11207 is a highly potent CXCR7 agonist.

VUF11207 is a highly potent CXCR7 agonist. VUF11207 induces recruitment of β-arrestin2 to the CXCR7 followed by internalization of the receptor.

VUF11207 is considered as a selective inhibitor of CXCR4 (C-X-C motif chemokine receptor 4).[1]

Sonstige Hinweise

Hygroscopic and light sensitive

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable