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S5761

Sigma-Aldrich

Natriumbicarbonat

Sodium bicarbonate

powder, BioReagent, for molecular biology, suitable for cell culture, suitable for insect cell culture

Synonym(e):

Natriumhydrogencarbonat, Natron

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500 G
€ 61,20
1 KG
€ 108,00
5 KG
€ 363,00

€ 61,20


Voraussichtliches Versanddatum25. März 2025


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500 G
€ 61,20
1 KG
€ 108,00
5 KG
€ 363,00

About This Item

Lineare Formel:
NaHCO3
CAS-Nummer:
Molekulargewicht:
84.01
Beilstein:
4153970
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12161702
PubChem Substanz-ID:
NACRES:
NA.75
Assay:
99.5-100.5%
Form:
powder
Löslichkeit:
water: soluble 100 mg/mL

€ 61,20


Voraussichtliches Versanddatum25. März 2025


Bulk-Bestellung anfordern

Qualität

for molecular biology
300

Qualitätsniveau

Produktlinie

BioReagent

Assay

99.5-100.5%

Form

powder

Methode(n)

cell culture | insect: suitable
cell culture | mammalian: suitable

pH-Wert

6.8-7.4

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

Löslichkeit

water: soluble 100 mg/mL

Dichte

2.16 g/mL at 25 °C (lit.)

SMILES String

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChIKey

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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Allgemeine Beschreibung

Natriumbicarbonat wird verbreitet als physiologischer Puffer in Zellkulturanwendungen eingesetzt. Der pKa-Wert für Bicarbonat <-> Carbonsäure-Reaktionen beträgt 6,4. Der pKa-Wert für Bicarbonat <-> Carbonat-Reaktionen beträgt 10,3. Natriumbicarbonat verfügt über zwei pKa-Werte: 6,4 und 10,3. Es wird verbreitet als physiologischer Puffer in In-vitro-Anwendungen eingesetzt.

Anwendung

Natriumbicarbonat wird verwendet:
  • als Komponente in Kultursystemen für Rinderembryonen während der In-vitro-Reifung, -Befruchtung und -Kultivierung (IVMFC)[1]
  • als Komponente von einer 1:1-Mischung von Dulbecco′s Modified Eagle′s Medium und Ham′s Nährstoffmischung F-12 bei der Kultivierung von bovinen mikrovaskulären Endothelzellen[2]
  • als Komponente von ITS (Insulin-Transferrin-Selenit)-Medium während der Isolierung von Dopamin-Neuronen aus humanen embryonalen Stammzellen[3]
  • als Komponente eines Mediums zur Kultivierung von humanen embryonalen Nierenzellen[4]
  • als Komponente von Beltsville-Auftaulösung zur Spermaverdünnung[5]

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Ähnliches Produkt

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Methods in molecular biology (Clifton, N.J.), 407, 311-322 (2008-05-06)
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Artikel

Nonylphenols (NP) are ubiquitous substances that have been detected in highly diverse foodstuff. As breakdown products of nonylphenol ethoxylates, NP could end up in the aquatic environment. This article presents a rapid method for NP detection in surface water by planar solid phase extraction – planar yeast estrogen screen (pSPE-pYES).

Questions

1–2 of 2 Questions  
  1. What is the size of his powder?

    1 answer
    1. The particle size of the powder has not been measured.

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  2. What is the shelf life after delivery and opening? Is there usually an impact on quality after 2 years? The color of the medium changed and the pH decreased. Does the solubility or function of sodium bicarbonate decrease as it gets older?

    1 answer
    1. This product is not assigned an expiration date. It is assigned a recommended retest date of approximately 5 years after the quality release date. A recommended retest date is the period of time during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications. For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

      After opening, various factors may influence the performance of the product. Moisture uptake and cross-contamination are common issues that are dependent on product handling and storage. If the product you are using is experience stability issues before the recommended restest date, this reporting should be investigated by our Technical Service team who can assist you with further troubleshooting and/or investigation. We kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Report Product Issues" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

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