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Merck

424455

Sigma-Aldrich

Resorufin

Dye content 95 %

Synonym(e):

7-Hydroxy-3H-phenoxazin-3-on, NSC 12097

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About This Item

Empirische Formel (Hill-System):
C12H7NO3
CAS-Nummer:
Molekulargewicht:
213.19
Beilstein:
174850
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12171500
PubChem Substanz-ID:
NACRES:
NA.47
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Form

powder

Qualitätsniveau

Zusammensetzung

Dye content, 95%

mp (Schmelzpunkt)

>300 °C (lit.)

λmax

573 nm

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

O=C(C=C1)C=C2C1=NC3=CC=C(O)C=C3O2

InChI

1S/C12H7NO3/c14-7-1-3-9-11(5-7)16-12-6-8(15)2-4-10(12)13-9/h1-6,14H

InChIKey

HSSLDCABUXLXKM-UHFFFAOYSA-N

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Allgemeine Beschreibung

Resorufin, a redox probe can be used to visualize cell respiration directly.[1] It is highly fluorescent and has an excitation maximum at 563nm and emission maximum at 587nm.[2]

Anwendung

Resorufin has been used in the measurements of hydrogen peroxide generation.[3]

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Malena B Rone et al.
Molecular endocrinology (Baltimore, Md.), 26(11), 1868-1882 (2012-09-14)
Steroid hormones are critical for organismal development and health. The rate-limiting step in steroidogenesis is the transport of cholesterol from the outer mitochondrial membrane (OMM) to the cytochrome P450 enzyme CYP11A1 in the inner mitochondrial membrane (IMM). Cholesterol transfer occurs
Hubert M Piwonski et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(22), E1437-E1443 (2012-05-09)
Enzymatic inhibition by product molecules is an important and widespread phenomenon. We describe an approach to study product inhibition at the single-molecule level. Individual HRP molecules are trapped within surface-tethered lipid vesicles, and their reaction with a fluorogenic substrate is
Yutaka Hitomi et al.
Analytical chemistry, 83(24), 9213-9216 (2011-11-18)
We developed a metal-based fluorescent probe for H(2)O(2) called MBFh1, which has an iron complex as a reaction site for H(2)O(2) and a 3,7-dihydroxyphenoxazine derivative as the fluorescent reporter unit. The iron complex reacts quickly with H(2)O(2) to form oxidants
Eyal Golub et al.
The Analyst, 136(21), 4397-4401 (2011-09-02)
Hemin/G-quadruplex catalyzes the H(2)O(2)-mediated oxidation of Amplex Red to the fluorescent product resorufin. This process is implemented to develop hairpin nucleic acid structures for the detection of DNA, to probe the catalytic activity of glucose oxidase, to use the thrombin-aptamer
Eduardo Vottero et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 16(6), 899-912 (2011-05-14)
CYP102A1, originating from Bacillus megaterium, is a highly active enzyme which has attracted much attention because of its potential applicability as a biocatalyst for oxidative reactions. Previously we developed drug-metabolizing mutant CYP102A1 M11 by a combination of site-directed and random

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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