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450243

Sigma-Aldrich

Natriumorthovanadat

99.98% trace metals basis

Synonym(e):

Trisodium vanadate

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€ 70,90
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10 G
€ 70,90
50 G
€ 207,00

About This Item

Lineare Formel:
Na3VO4
CAS-Nummer:
Molekulargewicht:
183.91
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12161600
PubChem Substanz-ID:
NACRES:
NA.22

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Qualitätsniveau

Assay

99.98% trace metals basis

Form

solid

Eignung der Reaktion

core: vanadium
reagent type: catalyst

mp (Schmelzpunkt)

850-866 °C (lit.)

SMILES String

[Na+].[Na+].[Na+].[O-][V]([O-])([O-])=O

InChI

1S/3Na.4O.V/q3*+1;;3*-1;

InChIKey

IHIXIJGXTJIKRB-UHFFFAOYSA-N

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Anwendung

Natriumorthovanadat (Na3VO4) kann als Metallvorläuferstoff Metallpräkursor in der Synthese von:
  • Vanadium-MCM-48 (V-MCM-48) durch die Anionenaustauschmethode eingesetzt werden. V-MCM-48 dient als Katalysator bei der Oxidation von Styrol zu Benzaldehyd.[1]
  • Nanorods von Vanadiumoxid-Partikeln werden mittels der Glykosidmethode untersucht.[2]
  • Yttrium-Vanadat (YVO4) wird mit kolloidales Europium dotiert.[3]

Biochem./physiol. Wirkung

Ein Inhibitor von Protein-Tyrosin-Phosphatasen, alkalischen Phosphatasen und ATPasen.
Hemmt ATPase, alkalische Phosphatase und Tyrosinphosphatase. Decavanadat, das bei saurem pH gebildet wird, hemmt die durch Inositol-1,4,5-Trisphosphat (IP3) induzierte Ca2+-Freisetzung aus endokrinen Zellen und blockiert die Bindung von IP3 an seinen Rezeptor im Hirngewebe.

Verpackung

Weist verschiedene biologische und physiologische Wirkungen im menschlichen Körper auf[4][5]

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Synthesis and characterization of TM-MCM-48 (TM= Mn, V, Cr) and their catalytic activity in the oxidation of styrene.
Gomez S, et al.
J. Catal., 233(1), 60-67 (2005)
Yu Hasegawa et al.
The Journal of pharmacology and experimental therapeutics, 317(2), 875-881 (2006-02-08)
Vanadium is widely distributed in the environment and exhibits various biological and physiological effects in the human body. We previously documented the neuroprotective effect of sodium orthovanadate (SOV) against in rodents i.v. injected with 2 ml/kg 50 mM SOV just
Glycothermal synthesis of assembled vanadium oxide nanostructures for gas sensing.
Fu H, et al.
Journal of Nanoparticle Research, 14(6), 871-871 (2012)
Synthesis and characterizations of YVO4: Eu colloids.
Huignard A, et al.
Chemistry of Materials, 14(5), 2264-2269 (2002)
Magdalena Malm et al.
Biotechnology journal, 9(9), 1215-1222 (2014-03-29)
Emerging strategies in cancer biotherapy include the generation and application of bispecific antibodies, targeting two tumor-associated antigens for improved tumor selectivity and potency. Here, an alternative format for bispecific molecules was designed and investigated, in which two Affibody molecules were

Questions

1–6 of 6 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the solubility of Product 450243, sodium orthovandate, and how do I store the solution?

    1 answer
    1. Solutions prepared as 1 mM in water (or higher if desired) and adjusted to pH 10 can be aliquotted in plastic tubes and stored at -20°C. To ensure the presence of monomers, solutions should be heated to boiling until translucent and pH re-adjusted to 10.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. What is Product 450243, Sodium orthovanadate, typically used for?

    1 answer
    1. This product can be used as a catalyst in chemical synthesis. It also utilized as an inhibitor of ATPase, alkaline phosphatase and tyrosine phosphatase.

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  6. For Product 450243, Sodium orthovanadate, what does metal basis purity mean?

    1 answer
    1. This product's purity is determined by ICP analysis. Trace metal impurities are analyzed, quantified and reported on the certificate of analysis for each lot/batch of product. The total metallic impurities are subtracted from 100% to result in the purity percentage based on metals.

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