S1563

SKF-86466 hydrochloride

solid, ≥98% (HPLC)

• Synonim(y): 6-Chloro-2,3,4,5-tetrahydro-3-methyl-1H-3-benzazepine hydrochloride
• Wzór liniowy: C₁₁H₁₄ClN·HCl
• Numer CAS: 86129-54-6
• Masa cząsteczkowa: 232.15
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278695
• MDL number: MFCD03453012
• Assay: ≥98% (HPLC)
• Form: solid

Właściwości

• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: H₂O: 24 mg/mL
• SMILES string: Cl.CN1CCc2cccc(Cl)c2CC1
• InChI: 1S/C11H14ClN.ClH/c1-13-7-5-9-3-2-4-11(12)10(9)6-8-13;/h2-4H,5-8H2,1H3;1H
• InChI key: JKQKVNMNAIFCFS-UHFFFAOYSA-N
• Gene Information: human ... ADRA2A(150), ADRA2B(151), ADRA2C(152)

Opis

Application

SKF 86466 was used to study adrenoceptor signaling in rat limbic seizure models.

Biochem/physiol Actions

SKF 86466 binds specifically to α2-adrenoceptors at pre- and post-junctional sites but was also reported to antagonize α1-aderenoceptors in humans. The structural similarity of receptors enables SKF 86466 binding to 5-HT1A receptors.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)