The solubility of this product can reach 10 mg/mL in water.
Kluczowe dokumenty
PHR1772
Meropenem
Pharmaceutical Secondary Standard; Certified Reference Material
Synonim(y):
Meropenem trihydrate, (1R,5S,6S)-2-[(3S,5S)-5-(dimethylaminocarbonyl)pyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-1-methylcarbapen-2-em-3-carboxylic acid trihydrate
Wybierz wielkość
1720,00 zł
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About This Item
1720,00 zł
Polecane produkty
klasa czystości
certified reference material
pharmaceutical secondary standard
Poziom jakości
agency
traceable to Ph. Eur. Y0001252
traceable to USP 1392454
rodzina API
meropenem
Certyfikat analizy
current certificate can be downloaded
opakowanie
pkg of 500 mg
metody
HPLC: suitable
gas chromatography (GC): suitable
Zastosowanie
pharmaceutical (small molecule)
Format
neat
temp. przechowywania
2-8°C
ciąg SMILES
O.O.O.C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)N(C)C)=C(N2C1=O)C(O)=O
InChI
1S/C17H25N3O5S.3H2O/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;;;/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);3*1H2/t7-,8-,9+,10+,11-,12-;;;/m1.../s1
Klucz InChI
CTUAQTBUVLKNDJ-OBZXMJSBSA-N
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Opis ogólny
Meropenem belongs to the class of a semi-synthetic 1β-methylcarbapenem antibiotics. It shows an extremely broad-spectrum of antibacterial performance and is known for its high stability against renal dehydropeptidase-I (DHP-I).[1]
Zastosowanie
Działania biochem./fizjol.
Komentarz do analizy
Inne uwagi
Przypis
produkt powiązany
Hasło ostrzegawcze
Danger
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Resp. Sens. 1 - Skin Sens. 1
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 3
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
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Certyfikaty analizy (CoA)
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumenty section.
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Klienci oglądali również te produkty
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What concentration of Meropenem PHR1772 add in aqueous solution
1 answer-
Helpful?
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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I'd like to know how I can solubilize this product (Meropenem PHR1772) and what is the solubility limit. Thanks in advance.
1 answer-
Meropenem is soluble in organic solvents and aqueous solutions. It is soluble in dimethyl sulfoxide (DMSO) at a concentration of approximately 30 mg/mL.
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Hello. May I know the potency of the product Meropenem PHR1772-500mg?
1 answer-
The purity of Meropenem, product PHR1772-500mg, is batch-specific. For example, batch number LRAB7853 is 71.1% pure (mass balance); 500 mg X 0.71 = 355 mg; 355,000 ug/500 mg = 710 ug/mg.
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How should be dissolved? Storage and stability after dissolving?
1 answer-
Product PHR1772, Meropenem, is sold as a certified reference material. It is typically used as described in either the United States Pharmacopeia (USP) or the European Pharmacopoeia (EP).
For the analysis for purity by HPLC, the USP recommends dissolving in a Triethylammonium phosphate buffer, pH 5.0; the recipe of the buffer is given in the USP. The USP goes on to recommend that the standard solution be stored in a refrigerator, and used with 24 hours.Helpful?
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