PHR1291

Cefazolin

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonim(y): Cefazolin, CFZ, Cephazolin
• Wzór empiryczny (zapis Hilla): C₁₄H₁₄N₈O₄S₃
• Numer CAS: 25953-19-9
• Masa cząsteczkowa: 454.51
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material; pharmaceutical secondary standard
• Poziom jakości: 300
• agency: traceable to Ph. Eur. C0682800; traceable to USP 1097603
• rodzina API: cefazolin
• Certyfikat analizy: current certificate can be downloaded
• opakowanie: pkg of 500 mg
• Zastosowanie: pharmaceutical
• Format: neat
• temp. przechowywania: 2-8°C
• ciąg SMILES: [s]1c(nnc1C)SCC2=C(N3[C@H](SC2)[C@@H](C3=O)NC(=O)C[n]4nnnc4)C(=O)O
• InChI: 1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1
• Klucz InChI: MLYYVTUWGNIJIB-BXKDBHETSA-N

Opis

Opis ogólny

Cefazolin is a first-generation cephalosporin β-lactam antibiotic drug that exhibits broad-spectrum antimicrobial activity against Klebsiella pneumoniae. It also acts in vitro against Gram-positive aerobic cocci while shows only a limited action on Gram-negative bacteria.[1][2]
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Zastosowanie

Cefazolin has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by thin layer chromatography-densitometry technique.[3]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Komentarz do analizy

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Inne uwagi

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Przypis

To see an example of a Certificate of Analysis for this material enter LRAB0131 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Polecane produkty

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H317,H334
• Zwroty wskazujące środki ostrożności: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Klasyfikacja zagrożeń: Resp. Sens. 1 - Skin Sens. 1
• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable