32138

Doripenem monohydrate

VETRANAL^®, analytical standard

• Synonim(y): (4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
• Wzór empiryczny (zapis Hilla): C₁₅H₂₄N₄O₆S₂ · H₂O
• Numer CAS: 364622-82-2
• Masa cząsteczkowa: 438.52
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329754061
• MDL number: MFCD09749887
• Beilstein/REAXYS Number: 15340136

Właściwości

• grade: analytical standard
• Quality Segment: 100
• product line: VETRANAL^®
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: [H]O[H].NS(NC[C@H](C1)NC[C@H]1SC2=C(C(O)=O)N3C([C@]([H])([C@H](O)C)[C@@]3([H])[C@H]2C)=O)(=O)=O
• InChI: 1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1
• InChI key: NTUBEBXBDGKBTJ-WGLOMNHJSA-N

Opis

General description

Doripenem belongs to the carbapenems family of β-lactam antibiotic compounds.[1]

Application

Doripenem monohydrate can be used as the precursor for the preparation of doripenem which may be used as an analytical reference standard for the determination of doripenem in:

• Bovine muscle by liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).[1]
• Bulk drug and formulations by high performance thin layer chromatography (HPTLC).
• Medicinal products by capillary electrophoresis coupled to ultraviolet (UV) detector as well as micellar electrokinetic chromatography (MEKC) with UV detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable