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P4347

Propylene Glycol

meets USP testing specifications

Propylene Glycol

Synonim(y):

1,2-Propanediol, 1,2-PDO, Methylethyl glycol, Propane-1,2-diol, Propylene glycol

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Do Państwa/SKUDostępnośćCena netto
500 mL
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1730,00 zł

Informacje o tej pozycji

Wzór liniowy:
CH3CH(OH)CH2OH
Numer CAS:
Masa cząsteczkowa:
76.09
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-338-0
Beilstein/REAXYS Number:
1340498
MDL number:
Bp:
187 °C (lit.)
Vapor pressure:
0.08 mmHg ( 20 °C)

1730,00 zł


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Quality Segment

agency

USP/NF, meets USP testing specifications

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

autoignition temp.

779 °F

expl. lim.

12.5 %

dilution

(for analytical testing)

refractive index

n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

application(s)

general analytical
pharmaceutical (small molecule)
sample preparation

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

General description

Propylene glycol, a low-molecular-weight aliphatic alcohol, holds significance as a key solvent in biological and pharmaceutical formulation research. Its outstanding miscibility with water and diverse organic compounds, coupled with its low freezing point, low vapor pressure, and non-toxic nature, positions it as a preferred choice for a variety of research applications, particularly in sensitive biological assays and pharmaceutical preparations.

Going beyond its solvent capabilities, propylene glycol excels as an excipient in pharmaceutical formulations, enhancing the solubility and stability of therapeutic molecules and pharmaceutical additives. This attribute proves indispensable in excipient and drug delivery research, contributing to the development of more efficacious and stable medications. In biochemical and physiological research, propylene glycol functions as a potent cryoprotectant, safeguarding cells and tissues from freezing-induced damage. Its application extends to investigations of drug absorption, metabolism, and distribution, providing researchers with a crucial tool to decipher the intricate journey of drugs within the body.

The versatility of propylene glycol extends to molecular biology, particularly in Polymerase Chain Reaction (PCR), where it safeguards DNA and RNA strands, ensuring reliable and reproducible results. Studies demonstrate its exceptional ability to stabilize DNA for extended periods, making it an essential component for long-term sample preservation in genetic and genomic analyses. In the pharmaceutical industry, propylene glycol finds extensive use as a solvent and extraction medium, playing a pivotal role in drug development research, facilitating efficient extraction and purification of bioactive compounds.

Application

Propylene glycol has been used:
  • for removing excess Oil Red O stain in zebrafish larvae
  • in the preparation of alginate hydrogels
  • for the dissolution of androstenone
  • for the calibration of cone beam scanner in computed tomography[1]

Features and Benefits

  • Versatile and adaptable for a wide variety of laboratory and research applications
  • Meets USP testing specifications

Other Notes

For additional information on our range of Biochemicals, please complete this form.
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Ta pozycja
PHR1051Y0001547W294004
application(s)

general analytical
pharmaceutical (small molecule)
sample preparation

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

flavors and fragrances

Quality Level

200

Quality Level

300

Quality Level

-

Quality Level

300, 400

density

1.036 g/mL at 25 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

mp

−60 °C (lit.)

mp

−60 °C (lit.)

mp

−60 °C (lit.)

mp

−60 °C (lit.)

expl. lim.

12.5 %

expl. lim.

12.5 %

expl. lim.

12.5 %

expl. lim.

12.5 %

autoignition temp.

779 °F

autoignition temp.

779 °F

autoignition temp.

779 °F

autoignition temp.

779 °F


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Klasa składowania

10 - Combustible liquids

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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