Przejdź do zawartości
Merck
Wszystkie zdjęcia(1)

Dokumenty

I114

Supelco

p-Iodoclonidine hydrochloride

analytical standard, for drug analysis

Synonim(y):

2-[(2,6-Dichloro-4-iodophenyl)imino]imidazoline hydrochloride

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
Wszystkie zdjęcia(1)

About This Item

Wzór empiryczny (zapis Hilla):
C9H8Cl2IN3 · HCl
Numer CAS:
108294-53-7
Masa cząsteczkowa:
392.45
Numer MDL:
MFCD00069292
Kod UNSPSC:
41116107
Identyfikator substancji w PubChem:
329815344
NACRES:
NA.24

klasa czystości

analytical standard, for drug analysis

Poziom jakości

100

Postać

solid

metody

HPLC: suitable
gas chromatography (GC): suitable

kolor

white to off-white

rozpuszczalność

H2O: soluble

Zastosowanie

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

ciąg SMILES

Cl[H].Clc1cc(I)cc(Cl)c1\N=C2/NCCN2

InChI

1S/C9H8Cl2IN3.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9;/h3-4H,1-2H2,(H2,13,14,15);1H

Klucz InChI

ULCGXOSKNHMYAX-UHFFFAOYSA-N

informacje o genach

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Zastosowanie

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Działania biochem./fizjol.

High affinity α2 adrenergic receptor agonist.
This page may contain text that has been machine translated.

Piktogramy

Exclamation mark
GHS07

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

H302 + H312 + H332

Klasyfikacja zagrożeń

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certyfikaty analizy (CoA)

Lot/Batch Number
118H4709

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

J E Piletz et al.
The Journal of pharmacology and experimental therapeutics, 267(3), 1493-1502 (1993-12-01)
Human platelets are shown to possess at least two high-affinity, imidazol(in)e-preferring binding sites that are pharmacologically distinct from alpha-2 adrenoceptors. These nonadrenergic sites were radiolabeled even in the presence of a 10 microM norepinephrine mask of alpha-2 adrenoceptors. Heterogeneity at
M A Gerhardt et al.
Molecular pharmacology, 38(2), 214-221 (1990-08-01)
The binding properties of p-[125I]iodoclonidine [( 125I]PIC) to human platelet membranes and the functional characteristics of PIC are reported. [125I]PIC bound rapidly and reversibly to platelet membranes, with a first-order association rate constant (kon) at room temperature of 8.0 +/-
P Ernsberger et al.
The Journal of pharmacology and experimental therapeutics, 264(1), 172-182 (1993-01-01)
Both the hypotension and the sedation elicited by centrally acting antihypertensive agents are traditionally attributed to activation of alpha 2 adrenergic receptors. Second-generation centrally acting agents such as moxonidine are less sedating but retain antihypertensive efficacy. A novel receptor which
Y Jin et al.
Investigative ophthalmology & visual science, 35(5), 2500-2508 (1994-04-01)
This study sought to identify and characterize subtypes of alpha 2-adrenoceptors in rabbit ciliary body. Radioligand binding assays were performed with the alpha 2-agonist ligand [125I]-p-iodoclonidine ([125I]PIC) and the antagonist ligand [3H]rauwolscine. Both [125I]PIC and [3H]rauwolscine bound to a single
D R Wallace et al.
European journal of pharmacology, 258(1-2), 67-76 (1994-06-02)
Binding characteristics of alpha 2-adrenoceptors in rat cerebral cortical membranes were compared using the antagonist radioligands [3H]idazoxan, [3H]2-(2-methoxy-1,4-benzodioxan-2-yl)-2-imidazoline ([3H]RX821002), and the partial agonist radioligand [125I]2-[2,6-(dichloro-4-iodophenyl)imino]imidazoline ([125I]iodoclonidine). With [3H]RX821002 and alpha 2-adrenoceptor subtype-selective competitors, both alpha 2A/D- and alpha 2C-adrenoceptor subtypes
Wyświetl wszystkie powiązane dokumenty

Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.

Skontaktuj się z zespołem ds. pomocy technicznej