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A-923

Supelco

Amitriptyline hydrochloride solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Wzór empiryczny (zapis Hilla):
C20H24ClN
Numer CAS:
549-18-8
Masa cząsteczkowa:
313.86
Numer WE:
200-659-6
Kod UNSPSC:
41116107
NACRES:
NA.24

klasa czystości

certified reference material

Postać

liquid

Właściwości

SNAP-N-SPIKE®, SNAP-N-SHOOT®

opakowanie

ampule of 1 mL

producent / nazwa handlowa

Cerilliant®

stężenie

1.0 mg/mL in methanol

metody

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Zastosowanie

clinical testing

format

single component solution

temp. przechowywania

−20°C

ciąg SMILES

Cl.CN(C)CC\C=C1\c2ccccc2CCc3ccccc13

InChI

1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

Klucz InChI

KFYRPLNVJVHZGT-UHFFFAOYSA-N

informacje o genach

human ... SLC6A2(6530) , SLC6A4(6532)

Powiązane kategorie

Opis ogólny

A Certified Spiking Solution® suitable for use in LC/MS or GC/MS applications in clinical toxicology, forensic analysis, urine drug testing, prescription monitoring or pharmaceutical research. Amitriptyline, marketed as the brand drug Elavil, Tryptizol, or Laroxyl, is a tricyclic antidepressant used in the treatment of major depression, clinical/endogenous depression and involutional melancholia.

Zastosowanie


  • Tricyclic antidepressant research: A study demonstrated the use of antisolvent precipitation to formulate excipient-free nanoparticles of psychotropic drugs, including amitriptyline hydrochloride, which could significantly impact the development of novel drug delivery systems for neuropharmacological applications (Wu and Wang, 2022).

  • Neuropharmacology amitriptyline: Research into micellar and interfacial phenomena of amitriptyline hydrochloride with cationic ester-bonded gemini surfactants explored its potential in enhancing drug solubility and stability, which is crucial for neuropharmacological studies and drug delivery systems (Abdul Rub, 2020).

  • Amitriptyline liquid formulation: A methodology to create polymeric nanocarriers containing hydrophilic low molecular-weight drugs, such as amitriptyline, offers a green strategy with very high drug loading, facilitating the development of amitriptyline-based formulations for pharmacological research (Villamizar-Sarmiento et al., 2019).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Opis
Cennik

A-085

Amitriptyline-d3 hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

N-902

Nortriptyline-D3 hydrochloride solution, 100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

N-907

Nortriptyline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

P-903

Protriptyline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

A-128

Amitriptyline N-ß-D-glucuronide solution, 100 μg/mL in acetonitrile: water (1:1), certified reference material, ampule of 1 mL, Cerilliant®

SMB00969

(E)-10-Hydroxy amitriptyline, ≥95% (HPLC)

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

H225,H301 + H311 + H331,H370

Klasyfikacja zagrożeń

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organy docelowe

Eyes,Central nervous system

Kod klasy składowania

3 - Flammable liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

49.5 °F - closed cup

Temperatura zapłonu (°C)

9.7 °C - closed cup

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

[Sweating under polypharmacy with tramadol, amitriptyline and duloxetine?].
Gesine Picksak et al.
Medizinische Monatsschrift fur Pharmazeuten, 36(5), 195-196 (2013-06-14)
Topical amitriptyline-ketamine for the treatment of brachioradial pruritus.
Timothy J Poterucha et al.
JAMA dermatology, 149(2), 148-150 (2013-02-22)
David Temesi et al.
Journal of pharmaceutical and biomedical analysis, 76, 164-168 (2013-01-22)
Procedures for drug monitoring based on Dried Blood Spot (DBS) sampling are gaining acceptance for an increasing number of clinical and preclinical applications, where ease of use, small sample requirement, and improved sample stability have been shown to offer advantages
Christian Janfelt et al.
Journal of mass spectrometry : JMS, 48(3), 361-366 (2013-03-16)
Displaced dual-mode imaging (DDI) is introduced as a method for simultaneous imaging in positive and negative-ion mode on the same sample with desorption electrospray ionization imaging, as well as a method for simultaneous imaging in full-scan and tandem mass spectrometry
Daniel J Stein et al.
The Annals of otology, rhinology, and laryngology, 122(1), 20-24 (2013-03-12)
We evaluated the safety and efficacy of amitriptyline hydrochloride in treating idiopathic chronic laryngeal irritability. A retrospective chart review identified patients treated with amitriptyline for laryngeal irritability in an academic otolaryngology practice. Subjects who had documented medication compliance and a
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