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Merck

803596

Sigma-Aldrich

BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)

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About This Item

Wzór empiryczny (zapis Hilla):
C16H20N2O7
Masa cząsteczkowa:
352.34
Numer MDL:
Kod UNSPSC:
12352200
Identyfikator substancji w PubChem:
NACRES:
NA.22

Próba

≥90%

Postać

powder

masa cząsteczkowa

352.34

przydatność reakcji

reagent type: cross-linking reagent

warunki przechowywania

desiccated

rozpuszczalność

water: soluble

Warunki transportu

ambient

temp. przechowywania

2-8°C

ciąg SMILES

O=C(C=CC1=O)N1CCOCCOCCOCCN2C(C=CC2=O)=O

InChI

1S/C16H20N2O7/c19-13-1-2-14(20)17(13)5-7-23-9-11-25-12-10-24-8-6-18-15(21)3-4-16(18)22/h1-4H,5-12H2

Klucz InChI

OYRSKXCXEFLTEY-UHFFFAOYSA-N

Opis ogólny

BM(PEG)2 and BM(PEG)3 are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e. oligomerization) or protein interactions. Because BM(PEG)2 and BM(PEG)3 have the same reactivity but differ in length, the relative success of these and similar reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.

Cechy i korzyści

  • Reactive groups: maleimide (both ends)
  • Reactive towards: sulfhydryl groups
  • Long, pegylated, sulfhydryl-to-sulfhydryl crosslinkers, composed of maleimide groups and 3-unit polyethylene glycol spacer arm
  • PEG spacers provide unique advantages, including enhanced solubility, increased stability, reduced tendency toward aggregation and reduced immunogenicity
  • Pure compounds with defined structure and molecular weight, ensuring reproducible protein-modification effects
  • Ideal for small molecule or peptide conjugations

Przestroga

This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
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Piktogramy

Exclamation mark

Hasło ostrzegawcze

Warning

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organy docelowe

Respiratory system

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


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