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Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 10,000, methoxy, hydroxyl

Synonim(y):

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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About This Item

Wzór liniowy:
CH3(OCH2CH2)nOH
Numer CAS:
9004-74-4
Numer MDL:
MFCD00084416
Kod UNSPSC:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) methyl ether, average Mn 10,000

gęstość pary

>1 (vs air)

ciśnienie pary

0.05 mmHg ( 20 °C)

Postać

chunks
powder or crystals

masa cząsteczkowa

average Mn 10,000

mp

60-65 °C

Mw/Mn

≤1.2

Ω-koniec

hydroxyl

α-koniec

methoxy

temp. przechowywania

−20°C

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

Klucz InChI

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Kod klasy składowania

10 - Combustible liquids

Klasa zagrożenia wodnego (WGK)

WGK 1

Temperatura zapłonu (°F)

415.0 °F - closed cup

Temperatura zapłonu (°C)

212.80 °C - closed cup

Certyfikaty analizy (CoA)

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Poly(ethylene glycol) average Mn 10,000, flakes

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Poly(ethylene glycol)

Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Prakash G Avaji et al.
Bioorganic & medicinal chemistry letters, 23(6), 1763-1767 (2013-02-16)
Saturated fatty acids (FA) were grafted using tyrosine as a spacer group to the cyclotriphosphazene ring along with equimolar hydrophilic methoxy poly(ethylene glycol) (MPEG) in cis-nongeminal way. Seven new cyclotriphosphazene amphiphiles were prepared from combinations of hydrophilic MPEGs with different
Robert K Delong et al.
Nanomedicine (London, England), 7(12), 1851-1862 (2012-09-05)
Nanoparticle conjugates have the potential for delivering siRNA, splice-shifting oligomers or nucleic acid vaccines, and can be applicable to anticancer therapeutics. This article compares tripartite conjugates with gold nanoparticles or synthetic methoxypoly(ethylene glycol)-block-polyamidoamine dendrimers. Interactions with model liposomes of a
Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
Pengxiang Zhao et al.
Chemical communications (Cambridge, England), 49(31), 3218-3220 (2013-03-14)
"Click" chemistry now offers access to a great variety of triazoles, and the first example of a strategy to stabilize gold nanoparticles (AuNPs) with a new 1,2,3-triazole-mPEG ligand is developed here together with preliminary examples of possible applications.
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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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