Przejdź do zawartości
Merck

KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1

Synonimy:
KIR1.1, ROMK, ROMK1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3758) Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(56379) potassium inwardly-rectifying channel, subfamily J, member 1
  • Rat(24521) potassium inwardly-rectifying channel, subfamily J, member 1
  • chicken(428236) potassium inwardly-rectifying channel, subfamily J, member 1
  • Horse(100072580) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic cat(101091140) potassium inwardly-rectifying channel, subfamily J, member 1
  • cow(539250) potassium inwardly-rectifying channel, subfamily J, member 1
  • dog(489285) potassium inwardly-rectifying channel, subfamily J, member 1
  • naked mole-rat(101720253) potassium inwardly-rectifying channel, subfamily J, member 1
  • domestic guinea pig(100722828) potassium inwardly-rectifying channel, subfamily J, member 1

Custom & Knockdown Gene Products

Small Molecule - Activator

Numer produktu
Opis
Gatunek
Diazoxide, ,
Gatunek
rat, mouse, human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Cromakalim, ,
Gatunek
rat
Glyburide, meets USP testing specifications,
Gatunek
rat, human
Glybenclamide, ≥99% (HPLC),
Gatunek
rat, human
Chlorpropamide, analytical standard, ≥97%,
Gatunek
human, mouse
Tolbutamide, analytical standard,
Gatunek
human, mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-KCNJ1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
dog, guinea pig, horse, human, rabbit, rat
Zastosowanie
western blot
Anti-KCNJ1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-KCNJ1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Gliclazide, powder, ≥98%,
Gatunek
human
Glipizide, solid,
Gatunek
human
Repaglinide, ≥98% (HPLC), solid,
Gatunek
human
Glimepiride, ≥98% (HPLC), solid,
Gatunek
human
Glyburide, meets USP testing specifications,
Gatunek
rat, human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Linopirdine, ≥98% (HPLC),
Gatunek
rat
VU591, ≥98% (HPLC),
Gatunek
human
Tertiapin-Q trifluoroacetate salt, ≥97% (HPLC),
Gatunek
rat, human, mouse
Chlorpropamide, analytical standard, ≥97%,
Gatunek
human, mouse
Tolbutamide, analytical standard,
Gatunek
human, mouse

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
Glipizide, solid,
Gatunek
human
Glimepiride, ≥98% (HPLC), solid,
Gatunek
human
Glybenclamide, ≥99% (HPLC),
Gatunek
rat, human
Chlorpropamide, analytical standard, ≥97%,
Gatunek
human, mouse

Small Molecule - Opener

Numer produktu
Opis
Gatunek
Minoxidil, ≥99% (TLC),
Gatunek
human
Diazoxide, ,
Gatunek
rat, mouse, human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human KCNJ1,
Gatunek
human