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Merck
모든 사진(1)

문서

860525P

Avanti

C24:1 Ceramide (d18:1/24:1(15Z))

Avanti Research - A Croda Brand

동의어(들):

N-nervonoyl-D-erythro-sphingosine

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About This Item

실험식(Hill 표기법):
C42H81NO3
CAS Number:
Molecular Weight:
648.10
UNSPSC 코드:
12352211
NACRES:
NA.25

형태

powder

포장

pkg of 1 × 10 mg (860525P-10mg)
pkg of 1 × 25 mg (860525P-25mg)
pkg of 1 × 5 mg (860525P-5mg)
pkg of 1 × 50 mg (860525P-50mg)

제조업체/상표

Avanti Research - A Croda Brand

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C42H81NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,40-41,44-45H,3-16,19-34,36,38-39H2,1-2H3,(H,43,46)/b18-17-,37-35+/t40-,41+/m0/s1

InChI key

VJSBNBBOSZJDKB-KPEYJIHVSA-N

일반 설명

Ceramides comprise spingolipids with acyl chains of C14 to C24 saturated and monounsaturated fatty acids. They are present in most of the mammalian tissues.

애플리케이션

C24:1 Ceramide (d18:1/24:1(15Z)) has been used as an internal stand in liquid chromatography-mass spectrometer. It is also suitable for use as a standard in high-performance liquid chromatography/tandem mass spectrometry.

생화학적/생리학적 작용

Ceramide (d18:1/24:1[15Z]) levels are elevated inprimary open angle glaucoma (POAG). It is a biomarker for the human arterial tissue and plasma major adverse cardiac and cerebrovascular events (MACE). In general, ceramides are key second messengers in sphingomyelin pathway and modulate the pathophysiology of metabolic diseases.

포장

5 mL Amber Glass Screw Cap Vial (860525P-10mg)
5 mL Amber Glass Screw Cap Vial (860525P-25mg)
5 mL Amber Glass Screw Cap Vial (860525P-50mg)
5 mL Amber Glass Screw Cap Vial (860525P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Plasma ceramides as prognostic biomarkers and their arterial and myocardial tissue correlates in acute myocardial infarction
de Carvalho LP, et al.
JACC. Basic to translational science, 3(2), 163-175 (2018)
Atypical surface behavior of ceramides with nonhydroxy and 2-hydroxy very long-chain (C28-C32) PUFAs
Penalva DA, et al.
Biochimica et Biophysica Acta - Biomembranes, 1838(3), 731-738 (2014)
Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism
Aljohani AJ, et al.
Investigative Ophthalmology & Visual Science, 55(6), 3413-3422 (2014)
Hypothalamic AMPK-ER stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance
Martinez-Sanchez N, et al.
Cell Metabolism, 26(1), 212-229 (2017)
Increased ceramide content and NFkappaB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males
Rivas DA, et al.
Journal of Applied Physiology, 113(11), 1727-1736 (2012)

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