860517P

C17 Ceramide (d18:1/17:0)

Avanti Research^™ - A Croda Brand

• 동의어(들): N-heptadecanoyl-D-erythro-sphingosine
• 실험식(Hill 표기법): C₃₅H₆₉NO₃
• CAS Number: 67492-16-4
• Molecular Weight: 551.93
• MDL number: MFCD02259275
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 10 mg (860517P-10mg); pkg of 1 × 25 mg (860517P-25mg); pkg of 1 × 5 mg (860517P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C35H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35(39)36-33(32-37)34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h28,30,33-34,37-38H,3-27,29,31-32H2,1-2H3,(H,36,39)/b30-28+/t33-,34+/m0/s1
• InChI key: ICWGMOFDULMCFL-QKSCFGQVSA-N

설명

일반 설명

Ceramide synthesis is mediated either by the salvage pathway by the acylation of sphingosine or sphingolipids hydrolysis or by de novo pathway via dihydroceramide formation.[1] Structurally, ceramides have a sphingoid base, a long-chain amino alcohol linked to fatty acid by an amide bond.[2]

애플리케이션

C17 Ceramide (d18:1/17:0) has been used:

• as an internal standard for myocardial ceramide quantification using chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry[3]
• as an internal standard in tandem mass spectrometry (MS/MS)[4]
• as a substrate for sphingomyelin synthase 2 enzyme[5]

생화학적/생리학적 작용

Ceramides play a key role in regulating various cellular processes like senescence and apoptosis.[1] They are directly involved in the proliferation and differentiation of skin cells and regulate skin barrier functionality.[2] Ceramide based analogs are potential anti-tumor agents and are regarded as tumor suppressor lipid.[6]

포장

5 mL Amber Glass Screw Cap Vial (860517P-10mg)

5 mL Amber Glass Screw Cap Vial (860517P-25mg)

5 mL Amber Glass Screw Cap Vial (860517P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3