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Merck
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문서

860678P

Avanti

C24 Ceramide-d7 (d18:1-d7/24:0)

Avanti Research - A Croda Brand 860678P, powder

동의어(들):

N-lignoceroyl-D-erythro-sphingosine (d7)

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About This Item

실험식(Hill 표기법):
C42H76D7NO3
CAS Number:
Molecular Weight:
657.16
UNSPSC 코드:
12352100
NACRES:
NA.25

형태

powder

포장

pkg of 1 × 1 mg (860678P-1mg)
pkg of 1 × 5 mg (860678P-5mg)

제조업체/상표

Avanti Research - A Croda Brand 860678P

배송 상태

dry ice

저장 온도

−20°C

일반 설명

C24 Ceramide (d18:1/24:0) is a synthetic ceramide containing sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide. C24 Ceramide-d7 (d18:1-d7/24:0) is a deuterated derivative of C24 Ceramide (d18:1/24:0).

애플리케이션

C24 Ceramide-d7 (d18:1-d7/24:0) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24 ceramide in skeletal muscle.

생화학적/생리학적 작용

C24 Ceramide plays a vital role in inducing cell death. Altered levels of C24 ceramide might be a potential indication in tumor monitoring. Determining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma helps to predict fatal outcome of coronary artery disease. The stable isotope form of C24 Ceramide (d18:1/24:0) is convenient for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.

포장

5 mL Amber Glass Screw Cap Vial (860678P-1mg)
5 mL Amber Glass Screw Cap Vial (860678P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

No data available

Flash Point (°C)

No data available


시험 성적서(COA)

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문서 라이브러리 방문

Yenisleidy de Las Mercedes Zulueta Díaz et al.
Colloids and surfaces. B, Biointerfaces, 185, 110621-110621 (2019-11-15)
L-ascorbic acid alkyl esters (ASCn) are lipophilic forms of vitamin C, which act as skin permeation enhancers. We investigated the physical changes induced by incorporating ASCn into stratum corneum (SC) lipid membranes and correlated this with the mechanism proposed in
Paul T Reidy et al.
The Journal of physiology, 596(21), 5217-5236 (2018-09-09)
Insulin sensitivity (as determined by a hyperinsulinaemic-euglyceamic clamp) decreased 15% after reduced activity. Despite not fully returning to baseline physical activity levels, insulin sensitivity unexpectedly, rebounded above that recorded before 2 weeks of reduced physical activity by 14% after the recovery
Hady Razak Hady et al.
Journal of clinical medicine, 8(12) (2019-12-18)
The liver plays a central role in the glucose and lipid metabolism. Studies performed on animal models have shown an important role of lipid accumulation in the induction of insulin resistance. We sought to explain whether in obese humans, the
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Luisa Coderch et al.
American journal of clinical dermatology, 4(2), 107-129 (2003-01-30)
Ceramides are the major lipid constituent of lamellar sheets present in the intercellular spaces of the stratum corneum. These lamellar sheets are thought to provide the barrier property of the epidermis. It is generally accepted that the intercellular lipid domain

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