おすすめの製品
アッセイ
≥98% (HPLC)
色
light brown to brown
溶解性
DMSO: >10 mg/mL
保管温度
2-8°C
SMILES記法
O.Oc1ccc2C(=O)c3ccc(O)c(O)c3Oc2c1O
InChI
1S/C13H8O6.H2O/c14-7-3-1-5-9(16)6-2-4-8(15)11(18)13(6)19-12(5)10(7)17;/h1-4,14-15,17-18H;1H2
InChI Key
ZFTTXYRPFMYDRT-UHFFFAOYSA-N
生物化学的／生理学的作用
3,4,5,6-Tetrahydroxyxanthone is a Na/K-ATPase inihibitor that inhibits pump function without activating the kinase signaling function.
3,4,5,6-Tetrahydroxyxanthone is a Na/K-ATPase inihibitor that inhibits pump function without activating the kinase signaling function. It inhibits Na/K ATPase pump action with an affinity comparable to ouabain, but does not alter Na or ATP affinity, is not blocked by potassium, and it does not activate the Src complex or downstream kinases.
調製ノート
3,4,5,6-Tetrahydroxyxanthone hydrate is soluble in DMSO at a concentration that is greater than 10 mg/ml.
シグナルワード
Danger
危険有害性情報
注意書き
危険有害性の分類
Acute Tox. 3 Oral
保管分類コード
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
T5955-5MG:
T5955-25MG:
T5955-BULK:
T5955-VAR:
T5955-IP:
最新バージョンのいずれかを選択してください：
Orhan Aktas et al.
The Journal of experimental medicine, 197(6), 725-733 (2003-03-12)
Statins, known as inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, exhibit numerous functions related to inflammation, such as MHC class II down-regulation, interference with T cell adhesion, and induction of apoptosis. Here we demonstrate that both subcutaneous and oral administration
Rodrigo Quezada et al.
Nanomaterials (Basel, Switzerland), 10(6) (2020-06-12)
Type of metal and metal-oxide NPs added to modify Thin-Film Composites Reverse Osmosis Membranes (TFC-RO) can alter their anti-biofouling properties by changing the dissolution process. The development of a mathematical model can facilitate the selection of these NPs. This work
M Armendariz Ontiveros et al.
Materials (Basel, Switzerland), 12(13) (2019-07-03)
The anti-biofouling and desalination properties of thin film composite reverse osmosis membranes (TFC-RO), modified by the incorporation of copper and iron nanoparticles, were compared. Nanoparticles of metallic copper (CuNPs) and an iron crystalline phase mix (Fe and Fe2O3, FeNPs) were
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