PZ0129

CP-380736

≥98% (HPLC)

• 別名: 6,7-ビス(2-メトキシエトキシ)-3,4-ジヒドロキナゾリン-4-オン, 6,7-ビス(2-メトキシエトキシ)-4(3H)-キナゾリノン, PF-00520893
• 実験式（ヒル表記法）: C₁₄H₁₈N₂O₅
• CAS番号: 179688-29-0
• 分子量: 294.30
• MDL番号: MFCD02678087
• UNSPSCコード: 51111800
• PubChem Substance ID: 329823716
• NACRES: NA.77

特性

• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: off-white to light tan
• 溶解性: DMSO: ≥10 mg/mL
• 保管温度: room temp
• SMILES記法: COCCOc1cc2N=CNC(=O)c2cc1OCCOC
• InChI: 1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
• InChI Key: PMQWTUWLIGJTQD-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

CP-380736は、上皮増殖因子受容体の選択的インヒビターです。

CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.

特徴および利点

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable