498289

3-エチニルアニリン

≥98%

• 化学式: HC≡CC₆H₄NH₂
• CAS番号: 54060-30-9
• 分子量: 117.15
• EC Number: 258-944-6
• MDL番号: MFCD00014779
• UNSPSCコード: 12352100
• PubChem Substance ID: 24873187
• NACRES: NA.22

特性

• 品質水準: 100
• アッセイ: ≥98%
• 反応適合性: reaction type: click chemistry
• 保管温度: 2-8°C
• SMILES記法: Nc1cccc(c1)C#C
• InChI: 1S/C8H7N/c1-2-7-4-3-5-8(9)6-7/h1,3-6H,9H2
• InChI Key: NNKQLUVBPJEUOR-UHFFFAOYSA-N

詳細

詳細

3-Ethynylaniline is a terminal alkyne that can be prepared by the reduction of 3-ethylnylnitrobenzene.[1]

アプリケーション

3-Ethynylaniline may be used in the synthesis of the following benzoxazine monomers:[2]

• bis{4-[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yloxy)]phenyl}phenylphosphino-1-one
• [3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazaperhydroin-6-yl)][3-(3-ethynylphenyl)(2H,4H-benzo[3,4-e]1,3-oxazin-6-yl)]phenylphosphino-1-one
• bis[3-(3-ethynylphenyl)(2H,4Hbenzo[3,4-e]1,3-oxazin-6-yl)oxy]phenylphosphino-1-one

It may be used:

• To synthesize succin(m-ethynyl)dianilide and sebaco(m-ethynyl)dianilide.[3]
• As a reagent in the multi-step synthesis of erlotinib hydrochloride.[4]
• To prepare 3-(3-ethynylphenyl)-6-methyl-2H, 4H-benzo[e]1,3-oxazine.[5]
• To prepare 3-[3-(4-acetylamino-benzyl)-[1,2,4]oxadiazol-5- yl]-N-(3-ethynyl-phenyl)-propionamide.[6]

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Warning
• 危険有害性情報: H226,H315,H319,H335
• 注意書き: P210 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 138.2 °F - closed cup
• 引火点(℃): 59 °C - closed cup
• 個人用保護具 (PPE): Eyeshields, Gloves, type ABEK (EN14387) respirator filter