D8668

2′-デオキシアデノシン 一水和物

powder, BioReagent, suitable for cell culture

• 別名: 9-(2-デオキシ-β-D-リボフラノシル)アデニン, アデニンデオキシリボシド
• 実験式（ヒル表記法）: C₁₀H₁₃N₅O₃ · H₂O
• CAS番号: 16373-93-6
• 分子量: 269.26
• Beilstein: 91015
• EC Number: 213-488-7
• MDL番号: MFCD00005754
• UNSPSCコード: 12352207
• PubChem Substance ID: 24894112
• NACRES: NA.75

特性

• 由来生物: synthetic (organic)
• 品質水準: 200
• 製品種目: BioReagent
• アッセイ: ≥99% (HPLC)
• フォーム: powder
• テクニック: cell culture | mammalian: suitable
• 溶解性: H₂O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
• 保管温度: 2-8°C
• SMILES記法: [H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
• InChI: 1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
• InChI Key: OLXZPDWKRNYJJZ-RRKCRQDMSA-N

詳細

アプリケーション

2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:

• To study the importance of homologous recombination at the interface between replication and mitosis
• To analyze deoxynucleoside-assisted transductions
• To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells

2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.

生物化学的／生理学的作用

Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves