P4722

ピリドキシン 塩酸塩

meets USP testing specifications

• 別名: PN HCl, アデルミン 塩酸塩, ビタミンB₆ 塩酸塩, ピリドキソール 塩酸塩
• 実験式（ヒル表記法）: C₈H₁₁NO₃ · HCl
• CAS番号: 58-56-0
• 分子量: 205.64
• Beilstein: 3632435
• EC Number: 200-386-2
• MDL番号: MFCD00012807
• UNSPSCコード: 12352205
• eCl@ss: 34058008
• PubChem Substance ID: 24898493
• NACRES: NA.21

特性

• 由来生物: synthetic (organic)
• 品質水準: 200
• 認証: USP/NF; meets USP testing specifications
• アッセイ: 98.0-102.0% dry basis
• フォーム: powder
• 色: white
• mp: 214-215 °C (lit.)
• アプリケーション: pharmaceutical (small molecule)
• SMILES記法: Cl[H].Cc1ncc(CO)c(CO)c1O
• InChI: 1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
• InChI Key: ZUFQODAHGAHPFQ-UHFFFAOYSA-N

詳細

詳細

Vitamin B group is water-soluble and exists in six forms namely the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate.[1] The food sources of vitamin B₆ include grains, nuts, fruits, vegetables and meat.[2]

アプリケーション

Pyridoxine hydrochloride has been used to test its neuroprotective functionality in traumatic brain injury (TBI) rats.[3] It has also been used as a reference standard to quantify vitamin B₆ in feed and digesta samples using high-performance liquid chromatography(HPLC).[4]

生物化学的／生理学的作用

Pyridoxine plays a key role in metabolism both carbohydrates and amino acids.[2] It supports brain development and its deficiency levels may lead to depletion of γ-aminobutyric acid (GABA) levels.[5] Pyridoxine catalyzes the neurotransmitter biosynthesis like dopamine and serotonin.[5] Pyridoxine in excess or deficient may lead to neuropathy.[6]

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Danger
• 危険有害性情報: H318
• 注意書き: P280 - P305 + P351 + P338
• 危険有害性の分類: Eye Dam. 1
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)