1.11714

3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide

for biochemistry

• 別名: 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide, Thiazolyl blue, MTT
• 実験式（ヒル表記法）: C₁₈H₁₆BrN₅S
• CAS番号: 298-93-1
• 分子量: 414.32
• MDL番号: MFCD00011964
• UNSPSCコード: 12352107
• EC Index Number: 206-069-5
• NACRES: NA.21

特性

• 品質水準: 100
• 形状: solid
• mp: 195 °C
• 溶解性: 10 g/L
• 保管温度: 2-30°C
• InChI: 1S/C18H16N5S.BrH/c1-13-14(2)24-18(19-13)23-21-17(15-9-5-3-6-10-15)20-22(23)16-11-7-4-8-12-16;/h3-12H,1-2H3;1H/q+1;/p-1
• InChI Key: AZKSAVLVSZKNRD-UHFFFAOYSA-M

詳細

アプリケーション

<ul>
<li><strong>Anal Biochem, 2017</strong>: Comparison of MTT and Neutral Red assays to assess cell viability in the presence of copper compounds, highlighting the versatility and sensitivity of the MTT assay in cytotoxicity testing (Gomez Perez et al., 2017).</li>
<li><strong>Indian J Pharmacol, 2016</strong>: Evaluation of the cytotoxic potential of various Indian fruit peels on liver cancer cells (HepG2) using MTT assay, providing insights into natural product research and potential anticancer properties (Garg et al., 2016).</li>
<li><strong>ACS Appl Mater Interfaces, 2015</strong>: Application in the real-time evaluation of live cancer cells, combining surface plasmon resonance and electrochemical methodologies with MTT assays for enhanced accuracy in viability testing (Wu et al., 2015).</li>
</ul>

アナリシスノート

Assay (argentometric): ≥ 98
Identity (IR-spectrum): passes test
Spec. Absorptivity A 1%/1cm (242 nm; 0.001 %; 1 cm; methanol): 480 - 530
Heavy metals (as Pb): ≤ 0.001 %
Sulfated ash: ≤ 0.5 %

安全性情報

• ピクトグラム: GHS07,GHS08
• シグナルワード: Warning
• 危険有害性情報: H315 - H319 - H335 - H341
• 注意書き: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable