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Merck

861847

Sigma-Aldrich

カルボニルシアニド 4-(トリフルオロメトキシ)フェニルヒドラゾン

97%

別名:

FCCP, メソキサロニトリル 4-トリフルオロメトキシフェニルヒドラゾン

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About This Item

化学式:
CF3OC6H4NHN=C(CN)2
CAS番号:
分子量:
254.17
Beilstein:
664446
EC Number:
MDL番号:
UNSPSCコード:
12352103

アッセイ

97%

mp

174-175 °C (dec.) (lit.)

SMILES記法

FC(F)(F)Oc1ccc(N\N=C(/C#N)C#N)cc1

InChI

1S/C10H5F3N4O/c11-10(12,13)18-9-3-1-7(2-4-9)16-17-8(5-14)6-15/h1-4,16H

InChI Key

BMZRVOVNUMQTIN-UHFFFAOYSA-N

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Lin Du et al.
Journal of natural products, 73(11), 1868-1872 (2010-10-12)
The mammea-type coumarin mammea E/BB (1) was found to inhibit both hypoxia-induced and iron chelator-induced hypoxia-inducible factor-1 (HIF-1) activation in human breast tumor T47D cells with IC(50) values of 0.96 and 0.89 μM, respectively. Compound 1 suppressed the hypoxic induction
A Magge et al.
Journal of applied microbiology, 106(3), 814-824 (2009-02-04)
To determine roles of coats in staining Bacillus subtilis spores, and whether spores have membrane potential. Staining by four dyes and autofluorescence of B. subtilis spores that lack some (cotE, gerE) or most (cotE gerE) coat protein was measured. Wild-type
Dawn A Delfín et al.
Bioorganic & medicinal chemistry, 17(2), 820-829 (2008-12-09)
BTB 06237 (2-[(2,4-dichloro-5-methylphenyl)sulfanyl]-1,3-dinitro-5-(trifluoromethyl) benzene), a compound previously identified through QSAR pharmacophore development and a virtual screen of the Maybridge database, possesses potent and selective activity against Leishmania parasites. In the present study, several analogs of BTB 06237 were synthesized and
Robin K Minor et al.
Scientific reports, 1, 70-70 (2012-02-23)
Sirt1 is an NAD(+)-dependent deacetylase that extends lifespan in lower organisms and improves metabolism and delays the onset of age-related diseases in mammals. Here we show that SRT1720, a synthetic compound that was identified for its ability to activate Sirt1
Sean Ekins et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(12), 2302-2308 (2010-09-17)
Drug-induced liver injury (DILI) is one of the most important reasons for drug development failure at both preapproval and postapproval stages. There has been increased interest in developing predictive in vivo, in vitro, and in silico models to identify compounds

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