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Merck

156124

Sigma-Aldrich

オキソン酸 カリウム塩

97%

別名:

4,6-ジヒドロキシ-1,3,5-トリアジン-2-カルボン酸 カリウム塩, アラントキサニン酸

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5 G
¥5,790
25 G
¥22,260
100 G
¥71,240

¥5,790


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サイズを選択してください

表示を変更する
5 G
¥5,790
25 G
¥22,260
100 G
¥71,240

About This Item

実験式(ヒル表記法):
C4H2KN3O4
CAS番号:
分子量:
195.17
EC Number:
MDL番号:
UNSPSCコード:
12352100
PubChem Substance ID:
NACRES:
NA.22

¥5,790


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品質水準

アッセイ

97%

mp

300 °C (lit.)

SMILES記法

[K+].[O-]C(=O)C1=NC(=O)NC(=O)N1

InChI

1S/C4H3N3O4.K/c8-2(9)1-5-3(10)7-4(11)6-1;/h(H,8,9)(H2,5,6,7,10,11);/q;+1/p-1

InChI Key

IAPCTXZQXAVYNG-UHFFFAOYSA-M

アプリケーション

オキソン酸カリウムはウリカーゼの阻害剤です。Sigmaの製品は、ラットでの抗腫瘍活性を失うことなく、5-フルオロウラシルで誘発された胃腸毒性の抑制に使用されています[1]。また、尿酸代謝を阻害するので、ラットで高尿酸血症を誘発する目的でも使用されています。[2]

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

156124-BULK:
156124-VAR:
156124-100G:
156124-25G:
156124-5G:


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T Shirasaka et al.
Cancer research, 53(17), 4004-4009 (1993-09-01)
The possibility of decreasing the gastrointestinal (GI) toxic effects of 5-fluorouracil (5-FU) on the digestive tract such as its injury of cells and induction of diarrhea, without reducing its antitumor activity, was investigated in rats. Oxonic acid was found to
Jieyu Zuo et al.
The Journal of pharmacy and pharmacology, 70(1), 124-132 (2017-10-24)
Traditional Chinese herbal formulas are difficult to be understood because of complex compositions and specific therapeutic principles. To better understand herbal compatibility in Traditional Chinese medicine (TCM), this study was conducted to investigate the effects of a Chinese pharmacopoeia-listed formula
Kei Nishizawa et al.
PloS one, 14(4), e0214862-e0214862 (2019-04-06)
The effects of hyperuricemia on the expression of kidney drug transporters and on the pharmacokinetics of several substrate drugs were examined. We first established a rat model of hyperuricemia without marked symptoms of chronic kidney failure by 10-day co-administration of
Haruka Fujikawa et al.
Antioxidants (Basel, Switzerland), 9(5) (2020-05-10)
The oxidant/antioxidant imbalance plays a pivotal role in the lung. Uric acid (UA), an endogenous antioxidant, is highly present in lung tissue, however, its impact on lung function under pathophysiological conditions remains unknown. In this work, pharmacological and genetic inhibition
Yasushi Habu et al.
Biochemical pharmacology, 69(6), 993-999 (2005-03-08)
We previously reported that in hyperuricemic rats, renal impairment occurred and organic ion transport activity decreased, accompanied with a specific decrease in the expression of rat organic anion transporters, rOAT1 and rOAT3, and organic cation transporter, rOCT2. In the present

質問

1–2/2 質問  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 回答
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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