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Merck

ESR2

estrogen receptor 2 (ER beta)

別名:
ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2100) Summary: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
  • Mouse(13983) estrogen receptor 2 (beta)
  • Rat(25149) estrogen receptor 2 (ER beta)
  • dog(403639) estrogen receptor 2 (ER beta)
  • chicken(395575) estrogen receptor 2 (ER beta)
  • domestic guinea pig(100731304) estrogen receptor 2 (ER beta)
  • Domestic Rabbit(100346748) estrogen receptor 2 (ER beta)
  • domestic cat(101086317) estrogen receptor 2 (ER beta)
  • Horse(100033964) estrogen receptor 2 (ER beta)
  • cow(281146) estrogen receptor 2 (ER beta)
  • Goat(100860823) estrogen receptor 2 (ER beta)
  • sheep(443066) estrogen receptor 2 (ER beta)

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Small Molecule - Activator

製品番号
詳細
Species
β-ニコチンアミドアデニンジヌクレオチド ナトリウム塩 from Saccharomyces cerevisiae, ,
Species
human
β-ニコチンアミドアデニンジヌクレオチド 水和物, ≥95% (HPLC),
Species
human
β-ニコチンアミドアデニンジヌクレオチド, pkg of 10 mg (per vial),
Species
human
β-ニコチンアミドアデニンジヌクレオチド 水和物, ≥96.5% (HPLC), ≥96.5% (spectrophotometric assay), from yeast,
Species
human
β-ニコチンアミドアデニンジヌクレオチド, pkg of 50 mg (per vial),
Species
human

Small Molecule - Agonist

製品番号
詳細
Species
ERB-041, ≥98% (HPLC),
Species
human
17α-Ethynylestradiol 3-cyclopentyl ether, ,
Species
human
エストロン, ≥99%,
Species
human, mouse, rat

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
ラロキシフェン 塩酸塩, United States Pharmacopeia (USP) Reference Standard,
Species
human
ラロキシフェン 塩酸塩, solid,
Species
human
リン酸エストラムスチンナトリウム, ,
Species
human
ラロキシフェン 塩酸塩, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
ラロキシフェン 塩酸塩, European Pharmacopoeia (EP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
フルベストラント, >98% (HPLC),
Species
human
2-メトキシエストラジオール, powder,
Species
human
フルベストラント, United States Pharmacopeia (USP) Reference Standard,
Species
human
フルベストラント, European Pharmacopoeia (EP) Reference Standard,
Species
human
システム適合性用フルベストラント, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Estrogen Receptor β Antibody, clone 68-4, rabbit monoclonal, clone 68-4, Upstate®, from rabbit,
交差性
human
アプリケーション
immunoprecipitation (IP)
western blot
Monoclonal Anti-ESR2 antibody produced in mouse, ,
交差性
human, monkey, mouse
アプリケーション
ChIP
dot blot

flow cytometry

immunocytochemistry

immunofluorescence

immunohistochemistry

western blot
Anti-Estrogen Receptor-β antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

western blot
Anti-Estrogen Receptor β Antibody, clone 9.88, clone 9.88, from mouse,
交差性
human, mouse, rat
アプリケーション
immunoprecipitation (IP)
western blot
抗ESR2抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
western blot

Cell Lines

製品番号
詳細
Species
MCF10A 細胞 ESR2 (-/-), ,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
α-エストラジオール, powder, ≥98% (TLC),
Species
human, rat
エストラジオール, meets USP testing specifications,
Species
human, mouse, rat
β-エストラジオール, BioReagent, powder, suitable for cell culture,
Species
human, mouse, rat
β-エストラジオール, ≥98%,
Species
human, mouse, rat
β-エストラジオール, powder, γ-irradiated, suitable for cell culture,
Species
human, mouse, rat

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human ESR2,
Species
human