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Nature methods, 8(9), 753-755 (2011-07-19)
Zinc-finger nucleases (ZFNs) have enabled highly efficient gene targeting in multiple cell types and organisms. Here we describe methods for using simple ssDNA oligonucleotides in tandem with ZFNs to efficiently produce human cell lines with three distinct genetic outcomes: (i)
Marine pollution bulletin, 114(2), 952-961 (2016-11-22)
Spatial and temporal patterns of coastal microbial pollution are not well documented. Our study examined these patterns through measurements of fecal indicator bacteria (FIB), nutrients, and physiochemical parameters in Hilo Bay, Hawai'i, during high and low river flow. >40% of
Oncotarget, 8(40), 67056-67081 (2017-10-06)
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic responses in lung cancer patients; however, the mechanisms involved in these responses have yet to be
Journal of microbiology (Seoul, Korea), 56(1), 11-23 (2018-01-05)
Protein glycosylation, the most universal and diverse post-translational modification, can affect protein secretion, stability, and immunogenicity. The structures of glycans attached to proteins are quite diverse among different organisms and even within yeast species. In yeast, protein glycosylation plays key
PloS one, 10(11), e0143447-e0143447 (2015-11-26)
The plant hormone salicylic acid (SA) controls several physiological processes and is a key regulator of multiple levels of plant immunity. To decipher the mechanisms through which SA's multiple physiological effects are mediated, particularly in immunity, two high-throughput screens were
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We offer over 200 custom DNA oligos modification for both DNA, RNA oligonucleotides and sequencing to probes for gene.
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オリゴヌクレオチドは、遺伝子検査、研究および法医学で使用される短いDNAまたはRNA分子です。カスタムオリゴは、ホスホロアミダイト法によって合成されます。カスタムオリゴ合成サービスに関するよくあるお問い合わせをご覧ください。
Custom oligonucleotide synthesis service FAQs address common queries on DNA and RNA molecule synthesis.
Label licenses for our oligonucleotide products, including Black Hole Quencher®, BlackBerry® Quencher, and Locked Nucleic Acid (LNA®).
We offer an easy-to-use Oligo Analyzer tool, OligoEvaluator™ that provides better primer dimer analysis values for PCR, and serves as an online oligonucleotide sequence calculator and Tm calculator.
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