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T8441

Sigma-Aldrich

L-Threonine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

Sinonimo/i:

(2S,3R)-2-Amino-3-hydroxybutyric acid

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25 G
163,00 €
100 G
496,00 €
1 KG
3.300,00 €

163,00 €


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Cambia visualizzazione
25 G
163,00 €
100 G
496,00 €
1 KG
3.300,00 €

About This Item

Formula condensata:
CH3CH(OH)CH(NH2)CO2H
Numero CAS:
Peso molecolare:
119.12
Beilstein:
1721646
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

163,00 €


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Nome del prodotto

L-Threonine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%

Origine biologica

non-animal source

agenzia

USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications

Nome Commerciale

BioXtra

Saggio

99.0-101.0%

Stato

powder

Qualità

meets EP, JP, USP testing specifications

tecniche

cell culture | mammalian: suitable

Impurezze

endotoxin, tested

Colore

white

Punto di fusione

256 °C (dec.) (lit.)

Solubilità

H2O: 1 g/10 mL, clear, colorless

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

C[C@@H](O)[C@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1
AYFVYJQAPQTCCC-GBXIJSLDSA-N

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Descrizione generale

L-Threonine is a naturally occurring amino acid belonging to the aspartate family of amino acids.[1]

Applicazioni

L-Threonine has been used for the following :
  • To study the effect of heat on homoserine kinase activity[2]
  • In Plackett–Burman analysis and then to study the effect of selected amino acids on monoclonal antibody production in CHO cells[3]
  • As a substrate to determine the L-threonine dehydrogenase activity[4]
  • To study the effect of L-Threonine on the growth rate of P. putida, to check for its tolerance towards L-Threonine[5]

Azioni biochim/fisiol

L-Threonine is considered to be an essential amino acid. L-Threonine is involved in the synthesis of mucin, a protein supporting intestinal function and integrity. L-Threonine is required for the performance of the immune system. It is also essential for O-linked glycosylation, protein phosphorylation and glycine synthesis.[6]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

Lot/Batch Number

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Regulation of L-Threonine Dehydrogenase in Somatic Cell Reprogramming
Chuanchun Han
Stem Cells, 31(5) (2013)
Systems metabolic engineering of Escherichia coli for L?threonine production.
Lee HK, et al.
Molecular Systems Biology, 3(1), 149-149 (2007)
Homoserine Kinase from Escherichia coli K-12: Properties,
Inhibition by L-Threonine, and Regulation of Biosynthesis
J. THEZE
Journal of Bacteriology, 118(2), 577-581 (1974)
Genome-wide identification of tolerance mechanisms toward p-coumaric acid in Pseudomonas putida
Patricia Calero
Biotechnology and Bioengineering, 115(3), 762-774 (2018)
Use of a Plackett-Burman statistical design to determine the effect of selected amino acids on monoclonal antibody production in CHO cells.
Gonzalez-Leal IJ
Biotechnol. Progress, 27(6), 1709-1717 (2011)

Domande

1–2 di 2 domande  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

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