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S4311

Sigma-Aldrich

L-Serine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications

Sinonimo/i:

L Serine, (S)-2-Amino-3-hydroxypropionic acid

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25 G
136,00 €
100 G
280,00 €
1 KG
1.440,00 €

136,00 €


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Cambia visualizzazione
25 G
136,00 €
100 G
280,00 €
1 KG
1.440,00 €

About This Item

Formula condensata:
HOCH2CH(NH2)CO2H
Numero CAS:
Peso molecolare:
105.09
Beilstein:
1721404
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

136,00 €


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Nome del prodotto

L-Serine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Origine biologica

non-animal source

agenzia

USP/NF
meets EP testing specifications
meets USP testing specifications

Saggio

98.5-101.0%

Stato

powder

tecniche

cell culture | mammalian: suitable

Impurezze

endotoxin, tested

Colore

white

Punto di fusione

222 °C (dec.) (lit.)

Solubilità

H2O: 50 mg/mL

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
MTCFGRXMJLQNBG-REOHCLBHSA-N

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Applicazioni

L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.[1][2]

Azioni biochim/fisiol

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.[3]
Precursor of glycine by serine hydroxymethyltransferase.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

Lot/Batch Number

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Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria
Taru Hilander
Nucleic Acids Research (2018)
Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe
Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System (2007)
Yurena Vivas-García et al.
Molecular cell, 77(1), 120-137 (2019-11-18)
Phenotypic and metabolic heterogeneity within tumors is a major barrier to effective cancer therapy. How metabolism is implicated in specific phenotypes and whether lineage-restricted mechanisms control key metabolic vulnerabilities remain poorly understood. In melanoma, downregulation of the lineage addiction oncogene
Kenji Hashimoto et al.
Progress in neuro-psychopharmacology & biological psychiatry, 29(5), 767-769 (2005-06-09)
Several lines of evidence suggest that D-serine, an endogenous agonist of the glycine site on the NMDA receptors, might play a role in the pathophysiology of schizophrenia. The purpose of this study was to determine whether levels of D- and

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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