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C6277

Sigma-Aldrich

Congo Red

Dye content, ≥85%, certified by the Biological Stain Commission, powder

Sinonimo/i:

Congo Red 4B, Cosmos Red, Cotton Red B, Cotton Red C, Direct Red 28, Direct Red R, Direct Red Y

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25 G
345,00 €

345,00 €


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Cambia visualizzazione
25 G
345,00 €

About This Item

Formula empirica (notazione di Hill):
C32H22N6Na2O6S2
Numero CAS:
Peso molecolare:
696.66
Colour Index:
22120
Beilstein:
3894858
Numero CE:
Numero MDL:
Codice UNSPSC:
12171500
ID PubChem:
NACRES:
NA.47

345,00 €


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Nome del prodotto

Congo Red, certified by the Biological Stain Commission, BioXtra

Grado

certified by the Biological Stain Commission

Nome Commerciale

BioXtra

Stato

powder

Composizione

Dye content, ≥85%

tecniche

microbe id | staining: suitable

Punto di fusione

>360 °C (lit.)

Solubilità

H2O: 10 mg/mL

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O

InChI

1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;
IQFVPQOLBLOTPF-HKXUKFGYSA-L

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Applicazioni

Congo red has been used for the staining of β amyloid peptides.[1][2][3]

Azioni biochim/fisiol

Congo red is a benzidine-based anionic diazo dye.[4] It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation.[5] Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.[6]

Compatibilità

Certified for use as a counterstain for alum based hematoxylin and in the Highman or the Churukian modification of Puchtler′s amyloid stain.

Pittogrammi

Health hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Carc. 1B - Repr. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


Elenchi normativi

Forniamo informazioni su eventuali restrizioni prevalentemente per i prodotti chimici. Per altre tipologie di prodotto siamo in grado di fornire soltanto informazioni limitate. Nessuna segnalazione significa che nessuno dei componenti è citato in un elenco. È dovere dell’utilizzatore assicurarsi che il prodotto venga impiegato in maniera sicura e a norme di legge.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.

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Certificati d'analisi (COA)

Lot/Batch Number

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Kinetic study and equilibrium isotherm analysis of Congo Red adsorption by clay materials.
Vimonses V, et al.
Chemical Engineering Journal, 148, 354-364 (2009)
Alejandro Llanos-Chea et al.
Journal of pediatric gastroenterology and nutrition, 68(4), 509-516 (2018-11-13)
Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance, a lack of effective vaccines, and accurate
Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses.
Berg I, et al.
Nature Protocols, 5, 935-935 (2010)
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
Sanan DA, et al.
The Journal of Clinical Investigation, 94, 860-860 (1994)
Long-term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of ?-secretase in a mouse model of Alzheimer's disease.
He P, et al.
PLoS ONE, 8, e55091-e55091 (2013)

Domande

1–3 di 3 domande  
  1. looking for Congo Red stain, the one used in histopathology, but not sure which of the options is the best.

    1 risposta
    1. The dry powder form allows for the preparation of Congo Red for various uses. The recommended dry dye for ordering is C6277 is currently undergoing BSC certification. Congo Red is a dye used for various staining procedures, mostly for staining of amyloid.

      Utile?

  2. Why does the SDS for Congo Red list carcinogen as an OSHA hazard, (Section 2) but in Section 11 on carcinogenicity, it states that there is no component identified as a carcinogen?

    1 risposta
    1. The reason that there is not an OSHA listing for carcinogens on most of SDS that have a hazard of a carcinogen hazard is because that section of the SDS is specifically for the OSHA regulated carcinogens, also referred to as the OSHA 13. Congo red at this time is not specifically called out  as a carcinogen by the other 3 Organizations listed (IARC, NTP, ACGIH) either. Congo red is listed by the European Classification Labeling & Packaging (CLP) Regulation (which is a pretty definitive guide for hazard classification), as a carcinogen. No other organizations have had the time to classify this material at this time. This is why it is only listed as a carcinogen in section 2 and in section 15.

      Utile?

  3. What is the Department of Transportation shipping information for this product?

    1 risposta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Utile?

Recensioni

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