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T4625

Sigma-Aldrich

Thiamine hydrochloride

reagent grade, ≥99% (HPLC)

Sinonimo/i:

Aneurine hydrochloride, Vitamin B1 hydrochloride

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5 G
20,30 €
10 G
29,40 €
25 G
39,10 €
100 G
149,00 €
250 G
280,00 €
1 KG
840,00 €

20,30 €


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Cambia visualizzazione
5 G
20,30 €
10 G
29,40 €
25 G
39,10 €
100 G
149,00 €
250 G
280,00 €
1 KG
840,00 €

About This Item

Formula empirica (notazione di Hill):
C12H17ClN4OS · HCl
Numero CAS:
Peso molecolare:
337.27
Beilstein:
3851771
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
34058006
ID PubChem:
NACRES:
NA.26

20,30 €


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Origine biologica

synthetic (organic)

Livello qualitativo

Grado

reagent grade

Saggio

≥99% (HPLC)

Stato

powder

tecniche

HPLC: suitable

Colore

white

Punto di fusione

250 °C (dec.) (lit.)

Solubilità

H2O: 50 mg/mL, clear, colorless

Stringa SMILE

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1
DPJRMOMPQZCRJU-UHFFFAOYSA-M

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Descrizione generale

Thiamine is a water-soluble vitamin-B complex. Structurally, it possesses a five-membered thiazolium ring and a six-membered amino-pyrimidine ring connected by a methyl group. Thiamine is naturally available in fruits, vegetables, poultry, eggs.[1]

Applicazioni

Thiamine hydrochloride has been used as a vitamin supplement to the holidic medium[2] and in bacterial growth medium.[3][4]

Azioni biochim/fisiol

Thiamine is an essential coenzyme in carbohydrate metabolism.[5] Deficiency of thiamine causes beriberi, a neurological and cardiovascular disease.[1] Thiamine is administered in case of deficiency, either due to reduced intake or synthesis.[5][1] Congenital defect in the thiamine transporter gene SLC19A2 causes thiamine-responsive megaloblastic anemia syndrome (TRMA). Thiamine mimics acetylcholine in brain and possible exerts a role in Alzheimer′s disease.[1] Thiamine deficiency in ruminants causes polioencephalomalacia.[5]

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

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I clienti hanno visto anche

Clinical and biological aspects of thiamine deficiency
Vitamins in the prevention of human diseases (2011)
Real-time in vitro measurement of GTP hydrolysis
Shutes A and Der CJ
Methods, 37(2), 183-189 (2005)
Applied Pharmacology for Veterinary Technicians (2009)
A holidic medium for Drosophila melanogaster
Piper MDW, et al.
Nature Methods, 11(1), 100-100 (2013)
Improved production of carotenes from synthetic medium by Blakeslea trispora in a bubble column reactor
Nanou K, et al.
Biochemical Engineering Journal, 67, 203-207 (2012)

Domande

1–2 di 2 domande  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 risposta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Utile?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 risposta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Utile?

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