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830856P

Avanti

17:0 PA

1,2-diheptadecanoyl-sn-glycero-3-phosphate (sodium salt), powder

Sinonimo/i:

PA(17:0/17:0)

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25 MG
193,00 €

193,00 €

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25 MG
193,00 €

About This Item

Formula empirica (notazione di Hill):
C37H72O8PNa
Numero CAS:
154804-54-3
Peso molecolare:
698.93
Numero MDL:
MFCD00214372
Codice UNSPSC:
51191904
NACRES:
NA.25

193,00 €

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Richiedi un ordine bulk

Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 25 mg (830856P-25mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 830856P

Tipo di lipide

cardiolipins
phospholipids

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[Na+].[P](=O)([O-])(OC[C@H](OC(=O)CCCCCCCCCCCCCCCC)COC(=O)CCCCCCCCCCCCCCCC)O

InChI

1S/C37H73O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-36(38)43-33-35(34-44-46(40,41)42)45-37(39)32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h35H,3-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/t35-;/m1./s1
IAELRFKIVVBNTO-RUQJKXHKSA-M

Descrizione generale

Phosphatidic acid (PA), a phospholipid is a minor component of the phospholipid pool. It is made up of two fatty acids and a phosphate group and are covalently attached with the help of ester linkage to a glycerol molecule. PA is an important constituent of cell membranes.[1]

Applicazioni

17:0 PA has been used as an internal standard for BXD liver samples/lipidomics analysis[2] and as an internal standard for BXD plasma sample analysis.[3] It may be used as a component in internal standard mix to spike the brain tissue homogenate.[4]

Azioni biochim/fisiol

Phosphatidic acid (PA) serves as a lipid messenger. It can enhance the production of muscle protein. PA can also serve as a signaling lipid. It plays a key role in mammalian target of rapamycin (mTOR) signaling.[1]

Confezionamento

5 mL Amber Glass Screw Cap Vial (830856P-25mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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Avanti

700186M

17:0 cholesteryl ester

Sophie Ayciriex et al.
Frontiers in molecular neuroscience, 10, 211-211 (2017-07-27)
Impairment in cholesterol metabolism is associated with many neurodegenerative disorders including Alzheimer's disease (AD). However, the lipid alterations underlying neurodegeneration and the connection between altered cholesterol levels and AD remains not fully understood. We recently showed that cholesterol accumulation in
Yoshibumi Shimizu et al.
Prostaglandins & other lipid mediators, 150, 106450-106450 (2020-04-17)
Cyclic phosphatidic acid (cPA) is a lysophospholipid mediator that suppresses cancer metastasis and osteoarthritis. It also has neuroprotective roles in diseases such as multiple sclerosis and delayed neuronal death following transient ischemia. In order to take advantage of the properties
Guillermo Escalante et al.
Journal of the International Society of Sports Nutrition, 13, 24-24 (2016-06-09)
Phosphatidic acid (PA) is a lipid messenger that has been shown to increase muscle protein synthesis via signaling stimulation of the mammalian target of rapamycin (mTOR). MaxxTOR® (MT) is a supplement that contains PA as the main active ingredient but
Emily L Gill et al.
Journal of proteome research, 19(1), 424-431 (2019-11-13)
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the brain, as well as the degeneration of motor and nonmotor circuitries. The cause of neuronal death is currently unknown, although chronic
Pooja Jha et al.
Cell systems, 6(6), 722-733 (2018-06-18)
The genetics of individual lipid species and their relevance in disease is largely unresolved. We profiled a subset of storage, signaling, membrane, and mitochondrial liver lipids across 385 mice from 47 strains of the BXD mouse population fed chow or
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