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Merck

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

Sinonimi:
5-HT4, 5-HT4R
Specie:
Human HTR4 (3360), Mouse Htr4 (15562), Rat Htr4 (25324), Horse HTR4 (100034053), domestic cat HTR4 (101088723), sheep HTR4 (101117928), cow HTR4 (317708), domestic guinea pig Htr4 (100135548), chicken HTR4 (416150), dog HTR4 (489198)
ID UniProtKB:
Q13639, Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199, Q9NY73
ID gene:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
SML1504
Tegaserod maleate, ≥98% (HPLC),
Specie
human
32473
Metoclopramide, VETRANAL®, analytical standard,
Specie
human
M1824990
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Specie
human
BP357
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Specie
human
M0763
Metoclopramide hydrochloride, solid,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
D9190
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
S3313
SB-204070 hydrochloride, solid, ≥97% (HPLC),
Specie
human
M7319
ML 10302, ≥98%, solid,
Specie
rat
G5918
GR 113808, ≥98% (HPLC), solid,
Specie
rat, human
32473
Metoclopramide, VETRANAL®, analytical standard,
Specie
human
M1824990
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
SAB4501480
Anti-5-HT-4 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunofluorescence
western blot
HPA040591
Anti-HTR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
SAB2101109
Anti-HTR4 antibody produced in rabbit, affinity isolated antibody,
Reattività con
dog, human, rabbit
Applicazione
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human
Z101
Zimelidine dihydrochloride, solid,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Specie
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Specie
human
F132
Fluoxetine hydrochloride, solid,
Specie
human
R0875
Reserpine, ,
Specie
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Specie
human

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Precursor

N° Catalogo
Descrizione
Specie
H9772
5-Hydroxy-L-tryptophan, powder,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EHU070651
MISSION® esiRNA, targeting human HTR4,
Specie
human