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M1824990

Metoclopramide

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide, Methoxychloroprocainamide

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About This Item

Formula empirica (notazione di Hill):
C14H22ClN3O2
Numero CAS:
364-62-5
Peso molecolare:
299.80
Beilstein:
1884366
Numero MDL:
MFCD00211338
Codice UNSPSC:
41116107
ID PubChem:
329817892
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

metoclopramide

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC

InChI

1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)
TTWJBBZEZQICBI-UHFFFAOYSA-N

Informazioni sul gene

human ... DRD2(1813) , HTR3A(3359) , HTR4(3360)

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Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Metoclopramide EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

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Metoclopramide impurity A, European Pharmacopoeia (EP) Reference Standard

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Metoclopramide Related Compound B, United States Pharmacopeia (USP) Reference Standard

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Metoclopramide Related Compound D, United States Pharmacopeia (USP) Reference Standard

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Metoclopramide Related Compound A, United States Pharmacopeia (USP) Reference Standard

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Metoclopramide Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2284

Metoclopramide Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2285

Metoclopramide Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2286

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PHR2287

Methyl 4-(Acetylamino)-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2506

Metoclopramide Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2507

Metoclopramide Impurity C, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2508

Methyl 4-Amino-2-hydroxybenzoate, Pharmaceutical Secondary Standard; Certified Reference Material

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

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Certificati d'analisi (COA)

Lot/Batch Number

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P Jay Pasricha et al.
Nature clinical practice. Gastroenterology & hepatology, 3(3), 138-148 (2006-03-03)
Metoclopramide, the only drug approved by the FDA for treatment of diabetic gastroparesis, but used off-label for a variety of other gastrointestinal indications, has many potentially troublesome adverse neurologic effects, particularly movement disorders. In this article, we comprehensively review the
Paul M Simpson et al.
Emergency medicine Australasia : EMA, 23(4), 452-457 (2011-08-10)
The objective of the present study was to conduct a systematic review and meta-analysis of randomized controlled trials, comparing metoclopramide with placebo, for preventing vomiting in patients who have received i.v. morphine for acute pain in the emergency setting, and
D E Reed et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 26(11), 1663-1668 (2014-09-30)
Intestinal transit assessment in mice using existing methods requires long recording periods or euthanization of animals to localize a tracer. We have developed a novel in vivo method to assess gastrointestinal (GI) transit in mice based on a clinically used
B M Mishriky et al.
British journal of anaesthesia, 108(3), 374-383 (2012-02-07)
Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea
Anna Maria Hibbs et al.
Pediatrics, 118(2), 746-752 (2006-08-03)
Metoclopramide is a commonly used drug to treat gastroesophageal reflux disease in infants. Given its widespread use and growing concern about toxicity in this population, we conducted a systematic review of metoclopramide for the treatment of gastroesophageal reflux disease in
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