Based on an online search, the use of zein in controlled release is typically for poorly water-soluble drugs. If that is the case, then this product may not be suitable for this purpose, as the solubility specification is 10 mg/mL in water, resulting in a clear solution. Purity by TLC is ≥ 98%.
F132
Fluoxetine hydrochloride
≥98% (TLC), solid, selective serotonin reuptake inhibitor
Sinonimo/i:
Fluoxetine HCl, (±)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine hydrochloride, LY-110,140 hydrochloride, Prozac®
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Cambia visualizzazione
| Taglio della confezione | SKU | Disponibilità | Prezzo |
|---|---|---|---|
| 10 mg | Disponibile per la spedizione OGGIdaSchnelldorf Distribution | 157,00 € | |
| 50 mg | Disponibile per la spedizione OGGIdaSchnelldorf Distribution | 376,00 € |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C17H18F3NO · HCl
Numero CAS:
Peso molecolare:
345.79
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
260-101-2
MDL number:
Form:
solid
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
Fluoxetine hydrochloride, solid
form
solid
Quality Segment
color
white
solubility
H2O: 4 mg/mL, DMSO: >5 mg/mL
originator
Eli Lilly
SMILES string
CNCCC(C1=CC=CC=C1)OC2=CC=C(C(F)(F)F)C=C2.[H]Cl
InChI
1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H
InChI key
GIYXAJPCNFJEHY-UHFFFAOYSA-N
Gene Information
General description
Application
Fluoxetine hydrochloride has been used to study its effect on the binding ability of the radiopharmaceutical 123I-labeled 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine ([123I]ADAM) to SERT (serotonin transporters) in mice.[2] It has also been used for the chronic treatment of light deprived animals.[3]It has also been used as a serotonin reuptake inhibitor to study its effects on acute stress in fish.[4]
Biochem/physiol Actions
Fluoxetine hydrochloride works at presynaptic terminals where it prevents the reuptake of serotonin, resulting in the accumulation of serotonin in extracellular fluid at synapses.[2]
Selective serotonin reuptake inhibitor; antidepressant.
Features and Benefits
This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Biogenic Amine Transporters and Chloride Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Legal Information
Sold under license from Eli Lilly and Company.
Prozac is a registered trademark of Eli Lilly and Co.
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Questo articolo | |||
|---|---|---|---|
| form solid | form - | form - | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 300 | Quality Level 100 |
| solubility H2O: 4 mg/mL, DMSO: >5 mg/mL | solubility - | solubility - | solubility methanol: 100 mg/mL, water: 5 mg/mL |
| color white | color - | color - | color - |
| Gene Information human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363), SLC6A4(6532) | Gene Information human ... SLC6A4(6532) | Gene Information human ... SLC6A4(6532) | Gene Information - |
| originator Eli Lilly | originator - | originator - | originator - |
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - STOT RE 2 - STOT SE 3
target_organs
Central nervous system
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Articoli
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DISCOVER Bioactive Small Molecules for Neuroscience
Contenuto correlato
Numero articolo commerciale globale
| SKU | GTIN |
|---|---|
| OP21-100UG | 04055977208931 |
| F132-10MG | 04061833611883 |
| F132-50MG | 04061835259656 |
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Good morning, can it be used for controlled release research with zein, and what would be its solubility and purity?
1 risposta-
Utile?
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What is the storage condition once I receive it?
1 risposta-
This product may be stored in room temperature.
Utile?
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What is the solubility of item F132, Fluoxetine hydrochloride? Also, how should stock solutions be stored after reconstitution?
1 risposta-
The solubility of Fluoxetine hydrochloride is as follows:
• Soluble in water: 3.46 mg/mL
•Soluble in DMSO: 34.58 ng/mL.After reconstitution, it is recommended to store stock solutions in tightly sealed vials at -20°C or below and to use them within 1 month.
Utile?
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Good day, I wanted to know if buying the 10 mg fluoxetine product would mean the customer would receive a pack of multiple 10 mg fluoxetine pills or if it means the product would just be 10 mg of the drug. Any information will be appreciated. Thank you.
1 risposta-
This product is in powder form and is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.
Utile?
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