Ugrás a tartalomra
Merck

SMB00436

Sigma-Aldrich

Pinoresinol diglucoside

≥98% (HPLC)

Szinonimák:

(+)-Pinoresinol 4,4′-O-bisglucopyranoside, Pinoresinol di-β-D-glucoside

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Tapasztalati képlet (Hill-képlet):
C32H42O16
CAS-szám:
Molekulatömeg:
682.67
MDL-szám:
UNSPSC kód:
12352205
PubChem Substance ID:
NACRES:
NA.25

Minőségi szint

Teszt

≥98% (HPLC)

form

powder

alkalmazás(ok)

metabolomics
vitamins, nutraceuticals, and natural products

tárolási hőmérséklet

−20°C

SMILES string

O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=CC=C([C@H]3OC[C@@]4([H])[C@]3([H])CO[C@@H]4C5=CC=C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)C(OC)=C5)C=C2OC)[C@@H]1O

InChI

1S/C32H42O16/c1-41-19-7-13(3-5-17(19)45-31-27(39)25(37)23(35)21(9-33)47-31)29-15-11-44-30(16(15)12-43-29)14-4-6-18(20(8-14)42-2)46-32-28(40)26(38)24(36)22(10-34)48-32/h3-8,15-16,21-40H,9-12H2,1-2H3/t15-,16-,21+,22+,23+,24+,25-,26-,27+,28+,29+,30+,31+,32+/m0/s1

Nemzetközi kémiai azonosító kulcs

ZJSJQWDXAYNLNS-FUPWJLLWSA-N

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Általános leírás

Pinoresinol diglucoside (PDG) is an important lignan found in the bark of the traditional Chinese medicinal plant Eucommia ulmoides, also known as Tu-Chung. It is also associated with other plants such as Forsythia suspensa and Styrax spp. In plants, PDG is produced through the phenylpropanoid pathway.
Pinoresinol diglucoside is an important lignan found in the bark of the Eucommia ulmoides, which is known in traditional Chinese medicine as du zhong. In plants, pinoresinol diglucoside is produced through the phenylpropanoid pathway.

Biokémiai/fiziológiai hatások

Pinoresinol diglucoside has antihypertensive properties. It serves as a α-glucosidase inhibitor. α-Glucosidase catalyzes the conversion of carbohydrates to glucose in the small intestine. Hence, pinoresinol diglucoside might be useful as an antidiabetic agent.
Pinoresinol diglucoside is a potent antihypertensive, anti-inflammatory and antioxidant agent. It also exerts tumor-suppressive and anti-osteoporotic properties. PDG serves as an α-glucosidase inhibitor that catalyzes the conversion of carbohydrates to glucose in the small intestine. Hence, it may serve as an antidiabetic agent in the management of diabetes. It displays neuroprotective properties by alleviating ischemic stroke-related brain injury in mice model.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Zhenhong Gao et al.
Journal of microbiology and biotechnology, 27(8), 1428-1440 (2017-06-18)
Phomopsis sp. XP-8 (an endophytic fungus) was previously found to produce pinoresinol diglucoside (PDG), a major antihypertensive compound of Tu-Chung (the bark of Eucommia ulmoides Oliv.), which is widely used in Chinese traditional medicines. In the present study, two bioconversion
M Harada et al.
Hinyokika kiyo. Acta urologica Japonica, 38(2), 207-211 (1992-02-01)
A rare case of ureteral endometriosis is reported. A 46-year-old nulliparous woman was referred to our hospital because of right hydronephrosis which was detected by ultrasonography; Drip infusion pyelography showed right hydroureteronephrosis with the distal obstruction. MRI demonstrated right ovarian
M Bulat et al.
The Journal of physiology, 275, 191-197 (1978-02-01)
1. After inhibition of 5-hydroxyindoleacetic acid (5-HIAA) transport by repeated administration of probenecid in cats, this acid accumulates linearly in the lumbosacral cord, lumbar cerebrospinal fluid (c.s.f.) and cisternal fluid during 5 hr of experiment. 2. A simple mathematical analysis
Bioconversion of pinoresinol diglucoside and pinoresinol from substrates in the phenylpropanoid pathway by resting cells of Phomopsis sp. XP-8
Zhang Y, et al.
PLoS ONE, 10(9), e0137066-e0137066 (2015)
Pinoresinol diglucoside is screened as a putative ?-glucosidase inhibiting compound in Actinidia arguta leaves
Kwon D, et al.
Journal of the Korean Society for Applied Biological Chemistry, 57(4) (2014)

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