SAB5702847

Anti-Coagulation factor III/Tissue Factor Antibody, clone 0W9Z8, Rabbit Monoclonal

• Szinonimák: CD142, TF, TFA
• UNSPSC kód: 12352203
• NACRES: NA.41
• klón: 0W9Z8, monoclonal
• application: WB
• faj reaktivitás: human, rat, rat
• technika/technikák: western blot: 1:500 - 1:2000

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• material: colorless
• klón: 0W9Z8, monoclonal
• Forma: liquid
• molekulatömeg: 45-53 kDa
• faj reaktivitás: human, rat, rat
• koncentráció: 0.5 mg/mL
• technika/technikák: western blot: 1:500 - 1:2000
• szín: colorless
• izotípus: IgG
• immunogén szekvencia: METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVK
• UniProt elérési szám: P13726
• kiszállítva: wet ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... F3(2152)

Leírás

Általános leírás

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Immunogén

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Coagulation factor III/Tissue Factor (P13726).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Alkalmazás

WB

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1