SAB5500082

Anti-Chromogranin A antibody, Rabbit monoclonal

clone SP12, recombinant, expressed in proprietary host, tissue culture supernatant

• UNSPSC kód: 12352203
• NACRES: NA.41
• konjugátum: unconjugated
• application: IHC
• klón: SP12, monoclonal
• faj reaktivitás: human (tested)
• citations: 3
• technika/technikák: immunohistochemistry: 1:200

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• rekombináns: expressed in proprietary host
• konjugátum: unconjugated
• antitest forma: tissue culture supernatant
• antitest terméktípus: primary antibodies
• klón: SP12, monoclonal
• faj reaktivitás: human (tested)
• faj reaktivitás (homológia által előrejelzett): bovine, pig
• technika/technikák: immunohistochemistry: 1:200
• izotípus: IgG
• UniProt elérési szám: P10645
• kiszállítva: wet ice
• tárolási hőmérséklet: 2-8°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... CHGA(1113)

Leírás

Általános leírás

Chromogranin A (CgA) is a circulating protein liberated by the neuroendocrine system. It is a glycoprotein that is located on human chromosome 14.

Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Immunogén

Recombinant protein encoding human chromogranin A.

Biokémiai/fiziológiai hatások

Chromogranin A (CgA) controls vascular physiology and angiogenesis. It modulates the storage and liberation of catecholamine via intracellular (vesiculogenic) and extracellular (catecholamine release–inhibitory) mechanisms. CHGA is essential to generate catecholamine secretory vesicles in chromaffin-lineage PC12 cells and is required to promote a regulated secretion system in nonsecretory cells.

Tulajdonságok és előnyök

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Fizikai forma

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable