SAB4700062

Monoclonal Anti-CD4-FITC , (N-terminal) antibody produced in mouse

clone MEM-241, purified immunoglobulin, buffered aqueous solution

• UNSPSC kód: 12352203
• NACRES: NA.44
• konjugátum: FITC conjugate
• application: FACS
• klón: MEM-241, monoclonal
• faj reaktivitás: human
• citations: 4
• technika/technikák: flow cytometry: suitable

Tulajdonságok

• biológiai forrás: mouse
• Minőségi szint: 100
• konjugátum: FITC conjugate
• antitest forma: purified immunoglobulin
• antitest terméktípus: primary antibodies
• klón: MEM-241, monoclonal
• Forma: buffered aqueous solution
• faj reaktivitás: human
• technika/technikák: flow cytometry: suitable
• izotípus: IgG1
• NCBI elérési szám: NM_000616.4
• UniProt elérési szám: P01730
• kiszállítva: wet ice
• tárolási hőmérséklet: 2-8°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... CD4(920)

Leírás

Általános leírás

Cluster of differentiation 4 (CD4) molecule is encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is mainly localized on the surface of specific leukocytes. CD4 is characterized with a four ecto-domains (D1-D4) of which D1, D2 and D4 contain disulfide bonds.

The antibody MEM-241 recognizes CD4 antigen, a 55 kDa transmebrane glycoprotein expressed on a subset of T lymphocytes ("helper" T-cells) and also on monocytes, tissue macrophages and granulocytes.

Immunogén

2 N-terminal domains of human CD4 fused to human IgG1 Fc

Alkalmazás

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

Biokémiai/fiziológiai hatások

Cluster of differentiation 4 (CD4) facilitates the activation of immunostimulatory T-cells. It serves as a primary receptor for human immunodeficiency virus (HIV)-1 entry. The encoded protein also plays a key role in altering cell elasticity. Elevated expression of soluble CD4 has been observed in patients of infectious and chronic inflammatory diseases and rheumatoid arthritis (RA). Thus, this protein can be used as a potential diagnostic marker for the development of RA.

Tulajdonságok és előnyök

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Fizikai forma

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable