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Merck
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SAB4300042

Sigma-Aldrich

Anti-phospho-AKT1 (pSer473) antibody produced in rabbit

affinity isolated antibody

Szinonimák:

Anti-AKT antibody produced in rabbit, Anti-MGC99656 antibody produced in rabbit, Anti-PKB antibody produced in rabbit, Anti-PKB-ALPHA antibody produced in rabbit, Anti-v-akt murine thymoma viral oncogene homolog 1 antibody produced in rabbit

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)

About This Item

UNSPSC kód:
12352203
NACRES:
NA.41

biológiai forrás

rabbit

Minőségi szint

100

konjugátum

unconjugated

antitest forma

affinity isolated antibody

antitest terméktípus

primary antibodies

klón

polyclonal

form

buffered aqueous solution

molekulatömeg

~60 kDa

faj reaktivitás

mouse, human, rat

koncentráció

1 mg/mL

technika/technikák

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

izotípus

IgG

immunogén szekvencia

(Q-F-SP-Y-S)

NCBI elérési szám

NP_001014431.1

UniProt elérési szám

P31749

kiszállítva

wet ice

tárolási hőmérséklet

−20°C

célzott transzláció utáni módosítás

phosphorylation (pSer473)

Géninformáció

human ... AKT1(207)

Immunogen

Peptide sequence around phosphorylation site of serine 473 (Q-F-S(p)-Y-S), according to the protein AKT1.

Tulajdonságok és előnyök

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Cél megnevezése

General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.

Fizikai forma

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Tárolási osztály kódja

10 - Combustible liquids

WGK

WGK 1

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Anti-phospho-AKT1 (pThr308) antibody produced in rabbit affinity isolated antibody

Sigma-Aldrich

SAB4504749

Anti-phospho-AKT1 (pThr308) antibody produced in rabbit

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