SAB3500310

Anti-IL-23 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Szinonimák: Anti-IL-27 p28, Anti-Interleukin-27
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 100
• konjugátum: unconjugated
• antitest forma: affinity isolated antibody
• antitest terméktípus: primary antibodies
• klón: polyclonal
• form: buffered aqueous solution
• molekulatömeg: predicted mol wt 21 kDa
• faj reaktivitás: human, mouse
• technika/technikák: immunocytochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBI elérési szám: AAH66268
• UniProt elérési szám: Q9NPF7
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... IL23A(51561)

Leírás

Általános leírás

IL-23 is a pro-inflammatory cytokine. It is mostly synthesized by activated DC (dendritic cells) and macrophages. It is a 20.7 kDa protein that has 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3.

Immunogen

IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23.

Alkalmazás

Anti-IL-23 antibody has been used in western blotting.

Biokémiai/fiziológiai hatások

The IL-23 plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity driving the expansion, stabilization and survival of Th17 cells.

Tulajdonságok és előnyök

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Kapcsolódás

The action of this antibody can be blocked using blocking peptide SBP3500310.

Fizikai forma

Supplied in PBS with 0.02% sodium azide.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable