S3523

Surfactin

from Bacillus subtilis, ≥98.0% (HPLC)

• Szinonimák: surfactin C
• Tapasztalati képlet (Hill-képlet): C₅₃H₉₃N₇O₁₃
• CAS-szám: 24730-31-2
• Molekulatömeg: 1036.34
• UNSPSC kód: 51102829
• PubChem Substance ID: 24899562
• NACRES: NA.85

Tulajdonságok

• biológiai forrás: Bacillus subtilis
• Minőségi szint: 200
• leírás: zwitterionic
• Teszt: ≥98.0% (HPLC)
• form: powder
• tárolási körülmény: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• szín: white to faint yellow
• CMC: 7.5-20 μmol/L (depending on methods)
• oldhatóság: ethanol: soluble 10 mg/mL
• antibiotikus hatásspektrum: Gram-negative bacteria; Gram-positive bacteria; fungi; mycoplasma; neoplastics; viruses
• Hatásmechanizmus: cell membrane | interferes
• tárolási hőmérséklet: 2-8°C
• SMILES string: CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1
• InChI: 1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1
• Nemzetközi kémiai azonosító kulcs: NJGWOFRZMQRKHT-WGVNQGGSSA-N

Leírás

Általános leírás

Chemical structure: peptide

Alkalmazás

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma.

Biokémiai/fiziológiai hatások

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes.

Egyéb megjegyzések

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)