S1542

Anti-Substance P antibody produced in rabbit

whole antiserum

• Szinonimák: Anti-SP
• MDL-szám: MFCD00162870
• UNSPSC kód: 12352203
• NACRES: NA.41

Tulajdonságok

• biológiai forrás: rabbit
• Minőségi szint: 200
• konjugátum: unconjugated
• antitest forma: whole antiserum
• antitest terméktípus: primary antibodies
• klón: polyclonal
• tartalmaz: 15 mM sodium azide
• faj reaktivitás: human, pig, bovine, rat, cat, monkey
• technika/technikák: dot blot: 1:20,000; radioimmunoassay: 1:5,000
• UniProt elérési szám: P20366
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• célzott transzláció utáni módosítás: unmodified
• Géninformáció: human ... TAC1(6863) ; rat ... Tac1(24806)

Leírás

Általános leírás

Substance P (SP) is a 11 amino acid peptide. It is a member of tachykinins family, that includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1 It is located on human chromosome 7q21.3.

Substance P (SP) is widely distributed throughout the central nervous system (CNS) and peripheral nervous system, including the brain, spinal cord, primary sensory neurons and intrinsic nerve fibers associated with the gastrointestinal (GI) tract.

Immunogen

synthetic Substance P (SP), conugated to KLH.

Alkalmazás

Anti-Substance P antibody has been used in immunostaining and immunohistochemistry.

Biokémiai/fiziológiai hatások

Substance P (SP) improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, trigger glandular secretion and controls autonomic reflexes. It plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.

Substance P (SP) is a neurotransmitter or neuromodulator. SP mediates the process of neurogenic inflammation.

Analízis megjegyzés

The antiserum is evaluated for activity and specificity by dot blot immunoassay and RIA.

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable