S0625

D-(−)-Salicin

≥99% (GC)

• Szinonimák: 2-(Hydroxymethyl)phenyl-β-D-glucopyranoside, Salicoside, Salicyl alcohol glucoside, Saligenin β-D-glucoside
• Tapasztalati képlet (Hill-képlet): C₁₃H₁₈O₇
• CAS-szám: 138-52-3
• Molekulatömeg: 286.28
• Beilstein: 89593
• EC-szám: 205-331-6
• MDL-szám: MFCD00006590
• UNSPSC kód: 12352205
• PubChem Substance ID: 24899442
• NACRES: NA.25

Tulajdonságok

• Minőségi szint: 200
• Teszt: ≥99% (GC)
• form: powder
• alkalmazás(ok): metabolomics; vitamins, nutraceuticals, and natural products
• SMILES string: OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O
• InChI: 1S/C13H18O7/c14-5-7-3-1-2-4-8(7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
• Nemzetközi kémiai azonosító kulcs: NGFMICBWJRZIBI-UJPOAAIJSA-N

Leírás

Általános leírás

Salicin is a non-phenolic glucosidic compound extracted from meadowsweet (Filipendula ulmaria L). It is majorly used as a substitute for quinine. Salicin can be used as a therapeutic for patients suffering from rheumatic fever. Salicin acts a metabolic precursor for salicylic acid. It is a novel phytochemical that exhibits immunological cross functions in plants and humans. Salicin facilitates growth and reproduction in plants. In addition, It also protects plants against biotic and abiotic stress.

Alkalmazás

D-(-)-Salicin has been used:

• to study its in vitro anticoagulant and antiplatelet activities
• as a standard in high performance liquid chromatography method (HPLC) for quantitation of salicin from willow plant
• as a tastant in taste threshold assay
• as a constituent of nutrient agar-salicin medium for selective isolation of Lactobacillus paracasei

Biokémiai/fiziológiai hatások

D-(−)-Salicin exerts anti-rheumatism and anti-inflammatory activities. It inhibits lipopolysaccharide (LPS) induced inflammation in in vitro and in vivo studies. It regulates different signaling pathways such as nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK). It also regulates cytokines concentration such as tumor necrosis factor-alpha(TNF-α), interleukin-1β, interleukin-6, and interleukin-10.

Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H317
• Óvintézkedésre vonatkozó mondatok: P280 - P302 + P352
• Veszélyességi osztályok: Skin Sens. 1
• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: dust mask type N95 (US), Eyeshields, Faceshields, Gloves