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Fontos dokumentumok
MAK107
LCAT Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Szinonimák:
Lecithin:cholesterol acyltransferase activity assay kit
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(2)
About This Item
Javasolt termékek
használat
sufficient for 100 fluorometric tests
alkalmazás(ok)
pharmaceutical
észlelési módszer
fluorometric
vonatkozó betegség(ek)
cardiovascular diseases
tárolási hőmérséklet
−20°C
Géninformáció
human ... LCAT(3931)
Általános leírás
The plasma protein lecithin:cholesterol acyltransferase (LCAT) catalyzes the transfer of an acyl group from the sn2 position of phosphatidylcholine to the 3-hydroxyl group of cholesterol resulting in the formation cholesteryl ester. This enzymatic activity occurs on the surface of high density lipoprotein (HDL). The cholesteryl esters formed by LCAT may be packed into the core of HDL.
Alkalmazás
Applications for this method include high-throughput screening, mechanism of action studies and structure-activity relationship (SAR) work.
LCAT Activity Assay Kit has been used for measuring lecithin-cholesterol acyl transferase activity in plasma samples.
Tulajdonságok és előnyök
Compatible with high-throughput handling systems.
Alkalmasság
Suitable for measuring phospholipase activity of LCAT in plasma or serum.
Elv
The LCAT Activity Assay Kit is a fluorometric assay useful for measuring phospholipase activity of (λEx=390 nm/λEm=470 nm) LCAT. The assay may be validated by inhibition of LCAT with iodoacetate or another spectrally benign (not Ellman′s reagent) LCAT inhibitor.
Analízis megjegyzés
Kit Components Only
Product No.
Leírás
- Substrate Reagent .1 mL
- READ Reagent 30 mL
- LCAT Assay Buffer 20 mL
Figyelmeztetés
Danger
Figyelmeztető mondatok
Óvintézkedésre vonatkozó mondatok
Veszélyességi osztályok
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Tárolási osztály kódja
3 - Flammable liquids
Lobbanási pont (F)
49.5 °F
Lobbanási pont (C)
9.7 °C
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