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Fontos dokumentumok

F7879

Sigma-Aldrich

Ferritin, cationized from horse spleen

10 mg/mL in 0.15 M NaCl

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

CAS-szám:
MDL-szám:
UNSPSC kód:
12352202
NACRES:
NA.26

biológiai forrás

horse spleen

Minőségi szint

sterilitás

sterile-filtered

form

liquid

koncentráció

10 mg/mL in 0.15 M NaCl

technika/technikák

cell culture | mammalian: suitable
electron microscopy: suitable

UniProt elérési szám

tárolási hőmérséklet

2-8°C

Géninformáció

horse ... FTL(100051593)

Általános leírás

Ferritin, an iron-storage protein is usually present in the liver and spleen in mammals. Iron and ferritin are distributed relatively same in the eye. Ferritin is made up of heavy and light chains.

Alkalmazás

A cationic derivative used to label negatively charged cell membranes for visualization by electron microscopy.
Ferritin is an iron storage protein that plays a central role in iron metabolism, and may be elevated in inflammatory or malignant diseases. It has been used in studies as an indicator of body iron supply, but may prove inaccurate in in the presence of chronic inflammation.
Ferritin, cationized from horse spleen has been used:
  • to incubate amoebae (106) in the study, to determine whether trophozoites are able to take up ferritin and internalise this protein for their growth in axenic culture
  • to determine phagosome-lysosome fusion by electron microscopy
  • to label freshly excised chick optic tecta in serum free incubation medium

Biokémiai/fiziológiai hatások

Ferritin holds iron at its ferric state (Fe3+). The core of ferritin has the capability to hold 4500 iron molecules. It is essential to store iron in vertebrates. Ferritin is also essential to store and transport iron in invertebrates. It plays a key role in dietary iron absorption.

Elkészítési megjegyzés

Prepared by coupling horse spleen ferritin with N,N-dimethyl-1,3-propanediamine (DMPA).

Tárolási osztály kódja

10 - Combustible liquids

WGK

WGK 2

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Dokumentumtár megtekintése

R H Adamson et al.
The Journal of physiology, 445, 473-486 (1992-01-01)
1. We have investigated the interaction of plasma proteins with the endothelial cell using cationized ferritin as a marker of the cell surface glycocalyx. 2. Single microvessels of the frog mesentery were sequentially perfused using glass micropipettes with solutions containing
Jennifer R Charlton et al.
American journal of physiology. Renal physiology, 321(3), F293-F304 (2021-07-21)
Kidney pathologies are often highly heterogeneous. To comprehensively understand kidney structure and pathology, it is critical to develop tools to map tissue microstructure in the context of the whole, intact organ. Magnetic resonance imaging (MRI) can provide a unique, three-dimensional
Fabrizio Bardelli et al.
Scientific reports, 7, 44862-44862 (2017-03-24)
Once penetrated into the lungs of exposed people, asbestos induces an in vivo biomineralisation process that leads to the formation of a ferruginous coating embedding the fibres. The ensemble of the fibre and the coating is referred to as asbestos
Interaction of Legionella pneumophila with Acanthamoeba castellanii: uptake by coiling phagocytosis and inhibition of phagosome-lysosome fusion.
Bozue J A and Johnson W
Infection and Immunity, 64(2), 668-673 (1996)
Jennifer R Charlton et al.
BMC nephrology, 24(1), 178-178 (2023-06-19)
A significant barrier to biomarker development in the field of acute kidney injury (AKI) is the use of kidney function to identify candidates. Progress in imaging technology makes it possible to detect early structural changes prior to a decline in

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